鼻中隔偏曲矫正术围手术期应用抗生素的临床意义

doi:10.6040/j.issn.1673-3770.0.2015.197

山东大学耳鼻喉眼学报 ›› 2015, Vol. 29 ›› Issue (6): 29-30.doi: 10.6040/j.issn.1673-3770.0.2015.197

鼻中隔偏曲矫正术围手术期应用抗生素的临床意义

付亚峰, 冯肖连, 林美芳, 龙朝庆

中山市小榄人民医院耳鼻咽喉头颈外科, 广东中山 528415

收稿日期:2015-05-22 出版日期:2015-12-16 发布日期:2015-12-16
作者简介:付亚峰. E-mail:yafeng216249@126.com

Evaluation the significance of antibiotics in septoplasty peri-operation duration

FU Yafeng, FENG Xiaolian, LIN Meifang, LONG Chaoqing

Department of Otorhinolaryngology & Head and Neck Surgery, Xiaolan Hospital of Southern Medical University, Zhongshan 528415, Guangdong, China

Received:2015-05-22 Online:2015-12-16 Published:2015-12-16

摘要/Abstract

摘要： 目的探讨鼻中隔偏曲矫正术围手术期预防性应用抗生素的临床意义.方法收集鼻中隔偏曲患者180例,随机分成三组,A组60例,围手术期不用任何抗生素;B组60例,术前30 min及术后3 d内静脉滴注头孢拉定(3.0 g);C组60例,术前30 min及术后3 d内静脉滴注头孢孟多酯(1.5 g),比较各组术后感染率.结果 A组感染6例(10.0%),B组感染7例(11.7%),C组感染5例(8.3%).三组患者术后感染率差异无统计学意义(χ²=0.370, P=0.831).结论鼻中隔偏曲矫正术围手术期常规预防性应用抗生素不能降低术后感染发生率,提示围术期可能不必要预防性应用抗生素.

关键词: 鼻中隔偏曲矫正术, 围手术期, 抗生素, 感染

Abstract: Objective To study the real necessity of antibiotics in septoplasties. Methods A total of 180 patients underwent septoplasty and were randomly divided into group A (n=60), group B (n=60) and group C (n=60). Group A was without antibiotics, group B and group C were respectively given cephradine(3.0 g) or cefamandole (1.5 g) both in the anesthesical induction and post-operatively for 3 days. Results There were 6 cases(10.0%) infected in group A, 7 cases(11.7%) infected in group B, and 5 cases(8.3%) infected in group C. The infection rate had no significant difference in the three groups (χ²=0.370, P=0.831). Conclusion In peri-operative period of septoplasty, routine prophylactic use of antibiotics can not reduce the incidence of post-operative infection.

Key words: Septoplasty, Infection, Antibiotics, Perioperation

中图分类号:

R765.9

付亚峰, 冯肖连, 林美芳, 龙朝庆. 鼻中隔偏曲矫正术围手术期应用抗生素的临床意义[J]. 山东大学耳鼻喉眼学报, 2015, 29(6): 29-30.

FU Yafeng, FENG Xiaolian, LIN Meifang, LONG Chaoqing. Evaluation the significance of antibiotics in septoplasty peri-operation duration[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(6): 29-30.

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鼻中隔偏曲矫正术围手术期应用抗生素的临床意义

Evaluation the significance of antibiotics in septoplasty peri-operation duration

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