自发性脑脊液耳漏的研究进展

doi:10.6040/j.issn.1673-3770.0.2018.431

摘要/Abstract

摘要： 自发性脑脊液耳漏是一类无明显颞骨创伤史、手术史、感染、肿瘤等原因的一类脑脊液耳漏。病理生理学目前尚不清楚,主要公认的有“先天性缺陷论”和“蛛网膜颗粒论”两种形成学说。成人和儿童漏口部位存在一定差异,常见于乳突天盖、鼓室盖、底板周围、窦脑膜角、内听道底、后颅窝等。该病临床表现不特异,不及时治疗严重者引起脑膜炎危及生命。行颞骨HRCT、葡萄糖定量及核素脑池显影等检查确诊后,应积极行手术治疗。

关键词: 脑脊液耳漏,自发性, 病因学, 诊断, 外科手术

Abstract: Spontaneous cerebrospinal fluid otorrhea(SCSFO)is a type of cerebrospinal fluid otorrhea that occurs without any of the obvious causes such as a history of temporal bone trauma or fracture, infection, or neoplasm. Two recognized but unverified theories have been proposed to explain its pathophysiology: congenital defect and arachnoid granulation. The leakage sites of SCSFO differ between young children and adults, and the common sites are the tegmen mastoid, tegmen tympani, and oval window. Though SCSFO is rare, it is an important cause of meningitis. For accurate diagnosis, we propose high-resolution computed tomography(HRCT)followed by a beta-2 transferrin and radionucleotide cisternogram. Surgical intervention is recommended.

Key words: Cerebrospinal and fluid otorrhea, spontaneous, Etiology, Diagnosis, Surgical procedures, operative

中图分类号:

R764.9

王玥,刘芊,王海波. 自发性脑脊液耳漏的研究进展[J]. 山东大学耳鼻喉眼学报, 2019, 33(2): 130-135.

WANG Yue, LIU Qian, WANG Haibo. Prospect and progress of spontaneous cerebrospinal fluid otorrhea[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(2): 130-135.

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