山东大学耳鼻喉眼学报 ›› 2020, Vol. 34 ›› Issue (1): 110-114.doi: 10.6040/j.issn.1673-3770.0.2019.454

• 综述 • 上一篇    下一篇

脐带血细胞分子水平检测与变应性疾病发病机制

芮晓清,李幼瑾   

  1. 上海交通大学医学院附属上海儿童医学中心 耳鼻咽喉科, 上海 200127
  • 出版日期:2020-01-20 发布日期:2020-03-06
  • 通讯作者: 李幼瑾. E-mail:kevinliyoujin@163.com
  • 基金资助:
    上海交通大学医工交叉研究基金项目(YG2016MS29)

Molecular level detection of umbilical cord blood cells and pathogenesis of allergic diseases

RUI Xiaoqing,LI Youjin   

  1. Department of Otolaryngology, Shanghai Children's Medical Center of Shanghai Jiaotong University School of Medicine, Shanghai 200127, China
  • Online:2020-01-20 Published:2020-03-06

摘要: 婴幼儿免疫状态改变可能是其以后患变应性疾病的早期征兆。脐带血检测能早期反映免疫状态水平,现成为研究变应性疾病发病机制的热点。对脐带血的细胞分子水平检测在变应性疾病发病机制研究中的应用价值做综述。

关键词: 变应性疾病, 脐带血, T细胞亚群, DNA甲基化, 维生素D

Abstract: Changes in immune status may be an early sign of subsequent allergic diseases in infants. Umbilical cord blood, as a reflection of early immune status, has become a hot research topic in the pathogenesis of allergic diseases. This article reviews the application value of umbilical cord blood at cellular and molecular level in the pathogenesis of allergic diseases.

Key words: Allergic disease, Umbilical cord blood, T cell subsets, DNA methylation, Vitamin D

中图分类号: 

  • R320
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