山东大学耳鼻喉眼学报 ›› 2020, Vol. 34 ›› Issue (6): 21-26.doi: 10.6040/j.issn.1673-3770.0.2019.537

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中药热奄包外敷联合七叶皂苷钠静滴治疗鼻部外伤肿胀疗效观察

张静祎1,2,王文一2,荣凌燕3,张家奎2,宋西成1   

  1. 1.青岛大学附属烟台毓璜顶医院 耳鼻咽喉头颈外科, 山东 烟台 264000;
    2.山东省文登整骨医院 耳鼻咽喉科, 山东 文登 264400;
    3.山东省文登整骨医院 药学部, 山东 文登 264400
  • 发布日期:2021-01-11
  • 通讯作者: 宋西成. E-mail:songxicheng@126.com

Curative effects of external application of traditional Chinese medicine in a hot salt bag combined with an intravenous drip of sodium aescinate in the treatment of nasal injury swelling

ZHANG Jingyi1,2, WANG Wenyi2, RONG Lingyan3, ZHANG Jiakui2, SONG Xicheng1   

  1. 1.Department of Otorhinolaryngology & Head and Neck Surgery, the Affiliated Yantai Yuhuangding Hospita1 of Qingdao University, Yantai 264000, Shandong, China;
    2.Department of Otorhinolaryngology, the Wendeng Osteopath Hospital, Wendeng 264400, Shandong, China;
    3.Department of Pharmacy, the Wendeng Osteopath Hospital, Wendeng 264400, Shandong, China
  • Published:2021-01-11

摘要: 目的 观察中药热奄包外敷联合七叶皂苷钠静滴治疗鼻部外伤肿胀的临床疗效。 方法 纳入2018年2月~2018年10月山东省文登整骨医院收治的新鲜鼻部软组织损伤患者56例,随机分为对照组与治疗组。所有患者伤后48 h内均采用伤处冷敷、七叶皂苷钠静滴治疗,48 h后对照组采用七叶皂苷钠静滴的基础上外敷空白热敷包治疗,治疗组在七叶皂苷钠静滴的基础上外敷中药热奄包治疗,疗程为6 d,观察两组肿胀消退时间和疼痛消失时间及两组肿胀消退的程度。 结果 肿胀消退时间:对照组(39.07±8.64)h、治疗组(32.79±7.89)h;疼痛消失时间:对照组(35.39±9.55)h、治疗组(28.25±7.32)h,两两相比均具有统计学意义(P<0.05)。治疗36 h后,对照组轻、中、重度肿胀分别为10、5、3例,10例肿胀完全消退;治疗组轻、中、重度肿胀分别为8、2、1例,17例肿胀完全消退,差异具有统计学意义(P<0.05)。 结论 中药热奄包外敷联合七叶皂苷钠静滴比空白热敷包外敷联合七叶皂苷钠静滴能更有效地促进鼻部肿胀的消退。

关键词: 热奄包, 鼻部外伤, 肿胀, 疼痛, 治疗结局

Abstract: Objective To study the curative effects of local external application of traditional Chinese medicine in a hot salt bag combined with a sodium aescinate intravenous drip for the treatment of nasal injury swelling. Methods Fifty-six patients with a fresh nasal soft tissue injury who were admitted to the Wendeng Osteopath Hospital between February 2018 and October 2018 were randomly divided into control and treatment groups. All patients were treated with a cold compress and a sodium aescinate intravenous drip within 48 h after the injury. Subsequently, treatment with a sodium aescinate intravenous drip combined with local external application of placebo in the control group and traditional Chinese medicine in the treatment group was performed for 6 days. The times it took for the swelling and pain to resolve were recorded. The grades and progression of swelling were also recorded. Results The time it took for the swelling to disappear was(39.07±8.64)h and(32.79±7.89)h in the control and treatment groups, respectively. The time it took for the pain to disappear was(35.39±9.55)h and(28.25±7.32)h in the control and treatment groups, respectively. The differences from pairwise comparisons were statistically significant(P<0.05). After 36 h of treatment, there were 10, 5, 3 and 10 control group cases, in contrast to 8, 2, 1, and 17 treatment group cases, of mild, moderate, severe, and resolved swelling, respectively. The differences were statistically significant(P<0.05). Conclusion The sodium aescinate intravenous drip showed better efficacy in the treatment of nasal injury swelling when combined with external application of traditional Chinese medicine, compared with placebo, in a hot salt bag.

Key words: Hot salt bag, Nasal injury, Swelling, Pain, Treatment outcome

中图分类号: 

  • R765
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