山东大学耳鼻喉眼学报 ›› 2020, Vol. 34 ›› Issue (6): 27-30.doi: 10.6040/j.issn.1673-3770.0.2019.588

• • 上一篇    

婴儿鼻腔软骨间叶性错构瘤2例及文献复习

陈坤,李磊,孟国珍,杨军,侯东明   

  1. 上海交通大学医学院附属新华医院 耳鼻咽喉头颈外科, 上海 200092
  • 发布日期:2021-01-11
  • 通讯作者: 侯东明. E-mail:houdongming@xinhuamed.com.cn

Nasal chondromesenchymal hamartoma in infants: A report of two cases and literature review

CHEN Kun,LI Lei, MENG Guozhen, YANG Jun, HOU Dongming   

  1. Department of Otolaryngology & Head and Neck Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
  • Published:2021-01-11

摘要: 目的 探讨婴儿鼻腔软骨间叶性错构瘤的临床及病理特点、诊断、治疗及预后。 方法 回顾性分析2016年5月至2019年3月上海交通大学医学院附属新华医院收治的2例经病理证实为鼻腔软骨间叶性错构瘤患儿的临床及病理资料,并对该病的诊断、治疗及预后进行探讨。 结果 起源于鼻腔或颅底的鼻腔软骨间叶性错构瘤经鼻内镜术完整切除,长期随访无复发。组织学显示间叶细胞及胶原纤维围绕软骨结构,呈良性增生特性。 结论 婴儿鼻腔软骨间叶性错构瘤临床表现多样且无特异性,早期诊断困难。鼻内镜手术是治疗鼻腔软骨间叶性错构瘤的主要手段,并且具有良好的临床效果。

关键词: 鼻腔软骨间叶性错构瘤, 鼻腔肿物, 小儿良性肿瘤, 鼻内镜切除, 颅底良性肿瘤

Abstract: Objective This study aimed to investigate the clinical and pathological features, diagnosis, treatment, and prognosis of nasal chondromesenchymal hamartoma(NCMH)in infants. Method We performed a retrospective analysis of the clinical and pathological data of two infants with NCMH admitted to the Xinhua Hospital affiliated with the Shanghai Jiao Tong University School of Medicine between May 2016 and March 2019. The diagnosis, treatment, and prognosis of the patients were also investigated. Results The NCMHs originated from the nasal cavity or skull base and were completely resected by nasal endoscopy. There was no recurrence in long-term follow-up. Histologically, the mesenchymal cells and collagen fibers showed benign hyperplasia around cartilage structures. Conclusion The clinical manifestations of infant NCMHs are diverse and non-specific; thus, early diagnosis is difficult. Nasal endoscopic surgery is the main treatment method for NCMH and has good clinical effects.

Key words: nasal chondromesenchymal hamartoma, nasal mass, pediatric benign tumors, endoscopic excision, skull base benign tumor

中图分类号: 

  • R765
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