青光眼患者睫状突位置测量及其临床意义

doi:10.6040/j.issn.1673-3770.0.2020.008

摘要/Abstract

摘要： 目的探讨原发性青光眼患者及正常人睫状突相对位置及其与眼部其他生物学参数的相关性,为经巩膜睫状体光凝精细化治疗提供研究资料。方法招募30例原发性青光眼患者和10例年龄匹配的正常对照人群。将青光眼患者分为3组,分别为原发性急性闭角型青光眼(APACG)组(10例),原发性慢性闭角型青光眼(CPACG)组(10例),原发性开角型青光眼(POAG)组(10例)。所有受试者行眼科A型超声及UBM检查,测量相关参数,包括房角开放距离(AOD)、小梁虹膜夹角(TIA)、小梁睫状突夹角(TCA)、睫状突高度(CBTmax)、睫状突体表投影位置(a)、前方深度(ACD)、晶体厚度(LT)、眼轴长度(AL)等眼前节生物学参数。结果对照组和POAG组在房角开放距离、小梁虹膜夹角及小梁睫状突夹角方面均大于APACG组和CPACG组(P<0.05),而对照组与POAG组之间、APACG组与CPACG组之间在房角开放距离、小梁虹膜夹角及小梁睫状突夹角方面的差异没有统计学意义。对照组的睫状突高度大于POAG组、APACG组及CPACG组(P<0.05),但是后三者的睫状突高度之间的差异无统计学意义。与正常对照组相比,APACG组的睫状体相对位置最靠前,CPACG组次之,差异均具有统计学意义;而POAG组与对照组在睫状突相对位置方面的差异无统计学意义。此外,前房深度、晶体厚度、眼轴长度、晶状体相对位置与房角开放距离、小梁虹膜夹角、小梁睫状突夹角以及睫状突体表投影位置之间有高度的相关性(P<0.001)。结论与原发性开角型青光眼患者及正常人相比,原发性闭角型青光眼患者睫状突体表投影位置偏前。利用UBM可以对青光眼患者睫状突进行定位,便于精确指导经巩膜睫状突光凝。

关键词: 睫状突位置, 眼前节参数, 超生生物显微镜

Abstract: Objective The study aimed to identify the correlation between the position of ciliary processes and other biological parameters in primary glaucoma patients and control group. These data may provide evidence for precise treatment in transscleral cyclophotocoagulation. Methods A total of thirty primary glaucoma patients and ten age matched healthy controls were enrolled in the study. Glaucoma patients were divided into 3 groups; acute primary angle closure glaucoma(APACG), chronic primary angle closure glaucoma(CPACG)and primary open angle glaucoma(POAG). All subjects underwent the A-scan and ultrasound biomicroscopy examinations. The parameters measured included angle open distance(AOD), trabecular-iris angle(TIA), trabecular-ciliary body process angle(TCA), ciliary body process height(CBTmax), the projected position of the ciliary body(a), anterior chamber depth(ACD), lens thickness(LT), axial length(AL). Results Both control group and POAG group are greater than APACG group and CPACG group in parameters of AOD、TIA and TCA, and the differences are statistically significant. However, the differences in AOD、TIA and TCA between control group and POAGand between APACG and CPACG were not statistically significant. The parameters of CBTmax in the control group was higher than that in the POAG, APACG, and CPACG groups(P<0.05), but the differences among POAG, APACG, and CPACG groups were not statistically significantly. Compared to the control group, the position of ciliary body in the APACG group was the most forward, followed by CPACG group, with statistically significant differences. However, the differences of ciliary body position between the POAG group and the control group were not statistically significantly. Furthermore, the parameters of ACD, LT, AL, and the len relative position were highly correlated with parameters of AOD, TIA, TCA, and the ciliary body projected position(P<0.001). Conclusion Compared with normal and POAG patients, the projected position of the ciliary body in PACG patients is forward. UBM can guide precise transscleral cyclophotocoagulation by positioning the ciliary process in glaucoma patients.

Key words: Ciliary body position, Parameters of anterior segment in eye, Ultrasound biomicroscop

中图分类号:

R775.9

赵栋栋,翟玉喜,路豪豪,张若晨,高建鲁. 青光眼患者睫状突位置测量及其临床意义[J]. 山东大学耳鼻喉眼学报, 2020, 34(6): 112-117.

ZHAO Dongdong, ZHAI Yuxi, LU Haohao, ZHANG Ruochen, GAO Jianlu. The position of ciliary processes in glaucoma patients and their clinical significance[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(6): 112-117.

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