山东大学耳鼻喉眼学报 ›› 2024, Vol. 38 ›› Issue (1): 66-71.doi: 10.6040/j.issn.1673-3770.0.2023.021

• 综述 • 上一篇    下一篇

透明质酸鼻部填充致单眼视网膜中央动脉阻塞1例并文献复习

李淑婷1,赵慧1,司明威1,崔文轩1,杨梦瑶1,王红2   

  1. 1. 山东大学 第一临床学院, 山东 济南 250012;
    2. 山东大学齐鲁医院 眼科, 山东 济南 250012
  • 发布日期:2024-01-12
  • 通讯作者: 王红. E-mail: dr.wanghong@163.com

Central retinal artery occlusion caused by facial filling with hyaluronic acid: a case report and literature review

LI Shuting1, ZHAO Hui1, SI Mingwei1, CUI Wenxuan1, YANG Mengyao1, WANG Hong2   

  1. 1. First Clinical College of Shandong University, Jinan 250012, Shandong, China2. Department of Ophthalmology Qilu Hospital of Shandong University, Jinan 250012, Shandong, China
  • Published:2024-01-12

摘要: 目的 通过1例透明质酸鼻部填充致单眼视网膜中央动脉阻塞(central retinal artery occlusion,CRAO)患者病例资料探讨其发病原因及治疗手段。 方法 患者鼻部注射透明质酸后右眼视力突然下降伴颞上方视物遮挡,当地医院治疗后来我院进行相关检查,给予药物及体外反搏治疗。 结果 治疗3 d后右眼矫正视力为0.15,眼底检查显示视盘水肿减轻,视盘周围水肿面积减小。 结论 CRAO是由视网膜中央动脉阻塞和对应视网膜区域血液供应不足引起的疾病,体外反搏具有无创治疗的优势,避免了有创治疗不良反应的发生,同时便于操作和推广,是CRAO的有效辅助治疗手段。

关键词: 视网膜中央动脉阻塞, 透明质酸, 体外反搏, 急性缺血性卒中

Abstract: Objective Through the case data of a patient with central retinal artery occlusion(CRAO)caused by hyaluronic acid filling in the nose, the study discusses the pathogenesis and treatment methods. Methods A female patient experienced a sudden loss of visual acuity with superior temporal visual obscuration in the right eye after receiving a nasal hyaluronic acid injection. After treatment at a local hospital, the patient came to our hospital for initial examination, and was treated with medication and external counterpulsation therapy. Results After 3 days of treatment, corrected visual acuity was 0.15 in the right eye; fundus examination showed enhanced optic disc edema and a decrease in the area of peripapillary white spots. Conclusion CRAO is a disease caused by central retinal artery occlusion and corresponding retinal nutrient supply deficiency. External counterpulsation has the distinction of being a non-invasive treatment(therefore avoiding the side effects of invasive treatment)and it is easy to administer and promote, and is an effective adjunctive treatment for CRAO.

Key words: Central retinal artery occlusion, Hyaluronic acid, Extracorporeal counterpulsation, Acute ischemic stroke

中图分类号: 

  • R765.21
[1] Callizo J, Feltgen N, Pantenburg S, et al. Cardiovascular risk factors in central retinal artery occlusion: results of a prospective and standardized medical examination[J]. Ophthalmology, 2015, 122(9): 1881-1888. doi:10.1016/j.ophtha.2015.05.044
[2] 杨培增,范先群.眼科学[M].9版.北京:人民卫生出版社, 2019: 188-191
[3] Hayreh SS, Podhajsky PA, Zimmerman MB. Retinal artery OcclusionAssociated systemic and ophthalmic abnormalities[J]. Ophthalmology, 2009, 116(10): 1928-1936. doi:10.1016/j.ophtha.2009.03.006
[4] Ammous I, Zhioua Braham I, EL Amri Mezghanni K, et al. Occlusion de l'artère centrale de la rétine révélant une endocardite infectieuse[J]. J Français D'ophtalmologie, 2018, 41(4): e167-e168. doi:10.1016/j.jfo.2018.01.001
[5] Kohara K, Ishikawa T, Kobayashi T, et al. Retinal artery occlusion during carotid artery stenting with distal embolic protection device[J]. Neuroradiol J, 2018, 31(5): 504-508. doi:10.1177/1971400918781990
[6] Taylor GI, Shoukath S, Gascoigne A, et al. The functional anatomy of the ophthalmic angiosome and its implications in blindness as a complication of cosmetic facial filler procedures[J]. Plast Reconstr Surg, 2020, 146(4): 745. doi:10.1097/prs.0000000000007155
[7] Tansatit T, Moon HJ, Apinuntrum P, et al. Verification of embolic channel causing blindness following filler injection[J]. Aesth Plast Surg, 2015, 39(1): 154-161. doi:10.1007/s00266-014-0426-z
[8] Beleznay K, Carruthers JDA, Humphrey S, et al. Avoiding and treating blindness from fillers[J]. Dermatol Surg, 2015, 41(10): 1097-1117. doi:10.1097/dss.0000000000000486
[9] Cohen JL, Biesman BS, Dayan SH, et al. Treatment of hyaluronic acid filler-induced impending necrosis with hyaluronidase: consensus recommendations[J]. Aesthet Surg J, 2015, 35(7): 844-849. doi:10.1093/asj/sjv018
[10] 王润生, 雷涛, 王毅, 等. 面部美容注射后眼动脉及脑动脉阻塞的临床特征分析[J]. 中华眼底病杂志, 2019, 35(5): 470-474. doi: 10.3760/cma.j.issn.1005-1015.2019.05.009 WANG Runsheng, LEI Tao, WANG Yi, et al. Analysis of clinical features of ophthalmic and cerebral artery occlusion after facial cosmetic injection[J]. Chinese Journal of Ocular Fundus Diseases, 2019, 35(5): 470-474. doi: 10.3760/cma.j.issn.1005-1015.2019.05.009
[11] 刘江, 文杭, 项敏泓. 玻尿酸注射致视网膜动脉阻塞1例[J]. 中国眼耳鼻喉科杂志,2020,20(6):491-492. doi:10.14166/j.issn.1671-2420.2020.06.020 LIU Jiang, WEN Hang, XIANG Minhong. A case of retinal artery obstruction caused by hyaluronic acid injection[J]. Chinese Journal of Otolaryngology, 2020, 20(6): 491-492. doi:10.14166/j.issn.1671-2420.2020.06.020
[12] 郝美玲,孙艳红,韦企平.头面部皮下注射药物致盲概述[J].中国中医眼科杂志, 2016, 26(6): 413-416. doi:10.13444/j.cnki.zgzyykzz.2016.06.018 HAO Meiling, SUN Yanhong, WEI Qiping. Overview of blinding by subcutaneous drug injection on the head and face[J]. Chinese Journal of Traditional Chinese Medicine and Ophthalmology, 2016, 26(6): 413-416. doi:10.13444/j.cnki.zgzyykzz.2016.06.018
[13] Lazzeri D, Agostini T, Figus M, et al. Blindness following cosmetic injections of the face[J]. Plast Reconstr Surg, 2012, 129(4): 995-1012. doi:10.1097/prs.0b013e3182442363
[14] Zheng H, Qiu L, Liu Z, et al. Exploring the possibility of a retrograde embolism pathway from the facial artery to the ophthalmic artery system in vivo[J]. Aesthetic Plast Surg, 2017, 41(5): 1222-1227. doi:10.1007/s00266-017-0877-0
[15] Ramesh S, Le AL, Katsev B, et al. The force required to inject a column of filler through facial arteries[J]. Dermatol Surg, 2020, 46(9): e32-e37. doi:10.1097/DSS.0000000000002248
[16] Bravo BS, Rocha CR, Bastos JT, et al. Comprehensive treatment of periorbital region with hyaluronic acid[J]. J Clin Aesthet Dermatol, 2015, 8(6): 30-35
[17] 黄明海,郭海科.视网膜中央动脉阻塞的临床治疗研究进展[J].国外医学(眼科学分册), 2004(4): 261-264
[18] 缪娜, 范玮. 视网膜中央动脉阻塞的治疗研究现状及进展[J]. 中华眼底病杂志, 2018, 34(3): 296-299. doi: 10.3760/cma.j.issn.1005-1015.2018.03.023 MIAO Na, FAN Wei. Clinical research status and progress of central retinal artery occlusion[J]. Chinese Journal of Ocular Fundus Diseases, 2018, 34(3): 296-299. doi: 10.3760/cma.j.issn.1005-1015.2018.03.023
[19] 谢礼丹, 张洪, 叶小琴. 基于卒中绿色通道静脉溶栓治疗视网膜分支动脉阻塞1例[J]. 中国中医眼科杂志, 2018, 28(5): 343-345. doi: 10.13444/j.cnki.zgzyykzz.2018.05.017 XIE Lidan, ZHANG Hong, YE Xiaoqin. A case of branch retinal artery occlusion treated by intravenous thrombolysis based on stroke green channel[J]. Chinese Journal of Chinese Ophthalmology, 2018, 28(5): 343-345. doi: 10.13444/j.cnki.zgzyykzz.2018.05.017
[20] 罗茂梅, 蔡善君. 血栓溶解法治疗视网膜中央动脉阻塞[J]. 国际眼科纵览, 2018, 42(6): 406-409. doi: 10.3760/cma.j.issn.1673-5803.2018.06.010 LUO Maomei, CAI Shanjun. Thrombolysis for central retinal artery occlusion[J]. International Review of Ophthalmology, 2018, 42(6): 406-409. doi: 10.3760/cma.j.issn.1673-5803.2018.06.010
[21] 朱爱玲. 视网膜动脉阻塞的治疗新进展[J]. 国外医学(眼科学分册), 1997(2): 90-93
[22] 陈嘉宝, 李金瑛. 视网膜动脉阻塞治疗现状[J]. 国际眼科纵览, 2019, 43(1): 68-72.doi: 10.3760/cma.j.issn.1673-5803.2019.01.014 CHEN Jiabao, LI Jinying. Treatment of retinal artery occlusion[J]. International Review of Ophthalmology, 2019, 43(1): 68-72.doi: 10.3760/cma.j.issn.1673-5803.2019.01.014
[23] Zhang L, Feng X, Shi HY, et al. Blindness after facial filler injections: the role of extravascular hyaluronidase on intravascular hyaluronic acid embolism in the rabbit experimental model[J]. Aesthet Surg J, 2020, 40(3): 319-326. doi:10.1093/asj/sjz280
[24] Carruthers J, Fagien S, Dolman P. Retro or PeriBulbar injection techniques to reverse visual loss after filler injections[J]. Dermatol Surg, 2015, 41(Suppl 1): S354-S357. doi:10.1097/dss.0000000000000558
[25] Lee A, Grummer SE, Kriegel D, et al. Hyaluronidase. Dermatol Surg[J]. 2010, 36(7): 1071-1077. doi: 10.1111/j.1524-4725.2010.01585.x
[26] 陈曦, 李珊珊, 赵露, 等.动脉溶栓治疗视网膜中央动脉阻塞Meta分析[J].山东大学耳鼻喉眼学报, 2020, 34(4): 28-34. doi: 10.6040 /j.issn.1673-3770.1.2020.057 CHEN Xi, LI Shanshan, ZHAO Lu, et al. Meta-analysis of arterial thrombolysis for central retinal artery obstruction[J]. Journal of Otolaryngology and Ophthalmology, Shandong University, 2020, 34(4): 28-34. doi: 10. 6040 /j.issn.1673-3770.1.2020.057
[27] Zhang LX, Lai LY, Zhou GW, et al. Evaluation of intraarterial thrombolysis in treatment of cosmetic facial filler-related ophthalmic artery occlusion[J]. Plast Reconstr Surg, 2020, 145(1): 42e-50e. doi:10.1097/prs.0000000000006313
[28] 刘雁庭, 姜奕, 张曦颖. 体外反搏治愈视网膜中央动脉阻塞一例[J]. 新疆钢铁, 1996(4): 10 LIU Yanting, JIANG Yi, ZHANG Xiying. A case of central retinal artery obstruction cured by extracorporeal counterpulsation[J]. Xinjiang Iron and Steel, 1996(4):10
[29] 廖瑞端,郭彦,张苗青,等.体外反搏早期治疗视网膜中央动脉阻塞1例[J]. 新医学, 1995(12): 641 LIAO Ruiduan, GUO Yan, ZHANG Miaoqing, et al. Early treatment of central retinal artery obstruction by extracorporeal counterpulsation in one case[J]. New Medicine, 1995(12): 641
[30] 黄红. 体外反搏治疗视网膜中央动脉阻塞二例[J].冶金医药情报,1993(5): 50 HUANG Hong. Two cases of central retinal artery obstruction treated with extracorporeal counterpulsation[J]. Metallurgical Medicine Information, 1993(5): 50
[1] 曹轩,肖旭平,李云秋. 透明质酸在慢性鼻窦炎中的研究进展[J]. 山东大学耳鼻喉眼学报, 2022, 36(3): 104-109.
[2] 陈曦, 李珊珊, 赵露, 尤冉, 王艳玲. 动脉溶栓治疗视网膜中央动脉阻塞Meta分析[J]. 山东大学耳鼻喉眼学报, 2020, 34(4): 28-34.
[3] 刘成,卫平存,胡金旺. 三种药物在泪囊鼻腔吻合术中的应用比较[J]. 山东大学耳鼻喉眼学报, 2011, 25(6): 58-.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!