山东大学耳鼻喉眼学报 ›› 2019, Vol. 33 ›› Issue (1): 33-37.doi: 10.6040/j.issn.1673-3770.1.2018.017

• 专家笔谈 • 上一篇    下一篇

特异性免疫治疗对过敏性鼻炎和哮喘的同步控制和远期疗效

邱前辉*(),高俊潇   

  1. 南方医科大学珠江医院耳鼻咽喉科，广东 广州 510282
  • 收稿日期:2018-09-21 出版日期:2019-01-20 发布日期:2019-01-28
  • 通讯作者: 邱前辉 E-mail:qiuqianhui@hotmail.com
  • 作者简介:邱前辉，医学博士，教授，主任医师，博士生导师。现任南方医科大学珠江医院耳鼻咽喉科主任。主要学术任职：中国医疗保健国际交流促进会过敏科学分会副主任委员，中华医学会变态反应学分会委员，中国中西医结合学会耳鼻咽喉科专业委员会变态反应专家委员会副主任委员，中国中西医结合学会耳鼻咽喉科专业委员会鼻颅底肿瘤和嗅觉专家委员会副主任委员，广东省医学会变态反应学分会主任委员，广东省医师协会变态反应工作委员会学术顾问，广东省医师协会耳鼻咽喉科医师分会鼻科专业组副组长，广东省医学会肿瘤学分会鼻咽癌学组组员，广东省医学会耳鼻咽喉科学分会鼻科学组组员，广东省自然科学基金、中国博士后基金、省医学科研基金评审专家。主要研究方向：鼻腔鼻窦炎症性疾病及颅底肿瘤的基础和临床研究。在广东省较早开展过敏性鼻炎过敏原检测和特异性免疫治疗，是国内首位开展变应性鼻炎标准化抗原冲击免疫治疗的专家，同时也是国内较早开展内镜下鼻窦炎手术以及内镜鼻颅底肿瘤手术的专家之一。主持国家和省部级课题15项，发表论文80余篇

Synchronous control and long-term efficacy of specific immunotherapy for allergic rhinitis and asthma

Qianhui QIU*(),Junxiao GAO   

  1. Department of Otorhinolaryngology, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong, China
  • Received:2018-09-21 Online:2019-01-20 Published:2019-01-28
  • Contact: Qianhui QIU E-mail:qiuqianhui@hotmail.com

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摘要：

近年来，过敏性鼻炎(AR)和哮喘的患病率呈明显增加的趋势。随着对特异性免疫治疗(SIT)的不断了解与深入，目前认为该方法可能是惟一通过调节免疫机制从而改变变应性疾病的自然进程，并且可以在治疗停止之后获得长期疗效。综述了SIT对AR和哮喘的同步控制和远期疗效，通过国内外文献回顾及分析对比，认为SIT在治疗AR和哮喘的过程中起着十分重要且积极的作用，并且能够预防AR向哮喘进展。但是，SIT也存在一些问题,值得进一步研究及探讨。

关键词: 变应性鼻炎, 哮喘, 特异性免疫治疗

Abstract:

In recent years, the prevalence of allergic rhinitis(AR)and allergic asthma has increased significantly. Because of a deeper understanding of specific immunotherapy(SIT), it is currently believed that SIT may be the only treatment that changes the natural course of allergic diseases by regulating the immune mechanisms and can maintain long-term effects after treatment has been discontinued. This article reviews the simultaneous control and long-term efficacy of SIT for AR and asthma. A literature review and analysis of domestic and international studies indicates that SIT plays an important and positive role in the treatment of AR and asthma and can prevent AR from progressing to asthma. However, SIT is also associated with some problems that merit further discussion.

Key words: Allergic rhinitis, Asthma, Specific immunotherapy

中图分类号: 

  • R765
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