J Otolaryngol Ophthalmol Shandong Univ ›› 2013, Vol. 27 ›› Issue (1): 24-25.doi: 10.6040/j.issn.1673-3770.0.2012.163

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Treatment of sudden hearing loss by monosialotetrahexosylganlioside

SHEN  Feng   

  1. Department of Otorhinolaryngology, Jiangsu Provincial Hospital of Traditional Chinese Medicine, Nanjing 210029, China
  • Received:2012-05-11 Published:2013-02-16

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Abstract:

Objective   To investigate the efficacy of monosialotetrahexosylganlioside in the treatment of sudden hearing lossl. Methods   80 cases suffered from sudden hearing loss were randomly divided into 2 groups. Except for glucocorticoid plus vasodilators and hyperbaric oxygen therapy, 40 cases in the treatment group were administrated with monosialotetrahexosylganlioside, while the other 40 cases in the control group were given mecobalamin injection. One course lasted for 10 days. Results   The total effective rates of hearing improvement between the treatment group and control group were 85% and 62.5%, while the cure rates of both groups were 52.5% and 27.5%(P<0.05).  Meanwhile, the total effective rate of tinnitus in the treatment and control group were 80% and 51.7%(P<0.05). Conclusion   Monosialotetrahexosylganlioside plays a positive role in the treatment of sudden hearing loss.

Key words: Monosialotetrahexosylganlioside, Tinnitus, Sudden hearing loss

CLC Number: 

  • R764
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