JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2014, Vol. 28 ›› Issue (5): 23-26.doi: 10.6040/j.issn.1673-3770.0.2014.045

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Intratympanic steroids to treat refractory sudden sensorineural hearing loss(52 cases report)

YAN Xiao-ling, MAO Min, ZHAI Jin-ming, CHEN Guan-gui, ZHANG Jian-guo, LIU Qi-ming, XUE Jin-ping   

  1. Department of Otolaryngology, the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, Guangdong, China
  • Received:2014-02-08 Published:2014-10-16

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Abstract: Objective To investigate the effect of intratympanic steroids as a salvage method to treat the patients with refractory sudden sensorineural hearing loss who did not respond to initial primary systemic steroid therapy. Methods Reviews were performed for 96 patients hospitalized between 2010 and 2013. Among them, 52 patients accepted intratympanic steroids injection, and the remaining 44 patients who refused intratympanic treatment were served as the control group. Mean air conduction at four frequencies (0.5, 1, 2, and 4 kHz) were monitored. Hearing results was compared before and 1 month after the treatment. Results Hearing improvement was defined as more than 10 dB in pure tone average(PTA). The hearing improvement was 30.8%(16 cases) in the intratympanic group but 6.8%(3 cases) in the control (P<0.01). Conclusion Intratympanic steroid injection is an effective therapy for sudden sensorineural hearing loss patients who are refractory to primary systemic steroid therapy.

Key words: Sudden sensorineural hearing loss, Salvage treatment, Intratympanic, Dexamethasone

CLC Number: 

  • R764.43
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