JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2018, Vol. 32 ›› Issue (3): 68-72.doi: 10.6040/j.issn.1673-3770.0.2018.044

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Influence of patient management on the clinical effect of sublingual dermatophagoides farinae drops in patients

WU Xiangping   

  1. Department of Otorhinolaryngology, Dongguan Kanghua Hospital, Dongguan 523080, Guangdong, China
  • Received:2018-01-16 Online:2018-05-20 Published:2018-05-20

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Abstract: Objective To analyze the influence of different patient management methods on the clinical effect and compliance to treatment with sublingual dermatophagoides farinae drops in patients with allergic rhinitis(AR). Methods One hundred and eighty patients with AR were randomly divided into a We-Media management Group(Group A, 90 patients)and a telephone management group(Group B, 90 patients). All patients were treated with sublingual immunotherapy(SLIT). In Group A, doctor-patient WeChat and/or QQ groups were formed. The doctor in charge acted as group leader, prepared monthly plans, sent to the patients SLIT-related information more than 3 times a week, and assessed patient reported outcome. In Group B, the patients were provided with on-the-spot demonstration and explanation and were followed up by telephone once every 3 month. We statistically analyzed dropout rates and the curative effect in the two groups at 1 year. Results The dropout rate in groups A and B was 13.3%(12/90)and 32.2%(29/90), respectively and the difference was statistically significant(χ2=9.128,P=0.003). The symptom scores before and after treatment were significantly different in both groups(P<0.05). There was no significant difference between Groups A and B before treatment(P>0.05), while the difference in the score of each symptom between the groups after treatment was significant(P<0.05). In Group A, the results were markedly effective in 15 patients(16.67%), effective in 49(54.44%), and ineffective in 26(28.89%), with a general effective rate of 71.11%(64/90). In Group B, the results were markedly effective in 13 patients(14.44%), effective in 26(28.89%), and ineffective in 51(56.67%), with a general effective rate of 43.33%(39/90). Conclusion The clinical effect and treatment compliance can be improved in patients with AR receiving SLIT by We-Media management.We-Media management is more advantageous especially in the long-term.

Key words: Allergic rhinitis, Sublingual immunotherapy, Patient management, We-Media, Clinical effect, Compliance

CLC Number: 

  • R765.4
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