Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2021, Vol. 35 ›› Issue (2): 114-118.doi: 10.6040/j.issn.1673-3770.0.2019.538

Previous Articles     Next Articles

Latest research progress of 3D printing technology and clinical applications in otorhinolaryngology

WANG Yanjie, CHENG FengliOverview,ZHAO ChangqingGuidance   

  1. Department of Otorhinolaryngology & Head and Neck Surgery, The Second Hospital, Shanxi Medical University/Key Research Lab of Airway neuroimmunology, Taiyuan 030001, Shanxi, China
  • Published:2021-04-20

PDF (PC)

322

Abstract: With advances of computer technology, the emergence of new materials, and the decline in production costs, 3D printing technology has been widely used in various medical processes, especially surgery. In the field of otolaryngology, 3D printing is mainly used in prosthesis manufacturing and implantation, preoperative planning, model reconstruction, surgical skills training, and medical education. Operation times is shortened and the goal of reducing costs can be achieved by using personalized implants and customized surgical instruments. Furthermore, surgical side injuries are reduced through preoperative planning and model exercises. In recent years, tissue-engineered grafts and the complex printing of viable tissues and organs have been explored as another potential application of 3D printing. This article mainly discusses the application and study prospect of 3D printing within the field of Otorhinolaryngology.

Key words: 3-Dimensional printing, Otolaryngology, Tissue Engineering, Digital model, Biomaterials

CLC Number: 

  • R762
[1] Hsieh TY, Cervenka B, Dedhia R, et al. Assessment of a patient-specific, 3-dimensionally printed endoscopic sinus and skull base surgical model[J]. JAMA Otolaryngol Head Neck Surg, 2018, 144(7): 574-579. doi:10.1001/jamaoto. 2018.0473.
[2] Reighard CL, Green K, Powell AR, et al. Development of a high fidelity subglottic stenosis simulator for laryngotracheal reconstruction rehearsal using 3D printing[J]. Int J Pediatr Otorhinolaryngol, 2019, 124: 134-138. doi:10.1016/j.ijporl. 2019.05.027.
[3] Hong CJ, Giannopoulos AA, Hong BY, et al. Clinical applications of three-dimensional printing in otolaryngology-head and neck surgery: a systematic review[J]. Laryngoscope, 2019, 129(9): 2045-2052. doi:10.1002/lary. 27831.
[4] He Y, Xue GH, Fu JZ. Fabrication of low cost soft tissue prostheses with the desktop 3D printer[J]. Sci Rep, 2014, 4: 6973. doi:10.1038/srep06973.
[5] Choi YD, Kim Y, Park E. Patient-specific augmentation rhinoplasty using a three-dimensional simulation program and three-dimensional printing[J]. Aesthet Surg J, 2017, 37(9): 988-998. doi:10.1093/asj/sjx046.
[6] Xu YH, Fan F, Kang N, et al. Tissue engineering of human nasal alar cartilage precisely by using three-dimensional printing[J]. Plast Reconstr Surg, 2015, 135(2): 451-458. doi:10.1097/PRS.0000000000000856.
[7] Visser J, Melchels FP, Jeon JE, et al. Reinforcement of hydrogels using three-dimensionally printed microfibres[J]. Nat Commun, 2015, 6: 6933. doi:10.1038/ncomms7933.
[8] Singh YP, Bandyopadhyay A, Mandal BB. 3D bioprinting using cross-linker-free silk-gelatin bioink for cartilage tissue engineering[J]. ACS Appl Mater Interfaces, 2019, 11(37): 33684-33696. doi:10.1021/acsami. 9b11644.
[9] Park JH, Park JY, Nam IC, et al. Human turbinate mesenchymal stromal cell sheets with bellows graft for rapid tracheal epithelial regeneration[J]. Acta Biomater, 2015, 25: 56-64. doi:10.1016/j.actbio. 2015.07.014.
[10] Chang JW, Park SA, Park JK, et al. Tissue-engineered tracheal reconstruction using three-dimensionally printed artificial tracheal graft: preliminary report[J]. Artif Organs, 2014, 38(6): E95-E105. doi:10.1111/aor.12310.
[11] Zhou GD, Jiang HY, Yin ZQ, et al. In vitro regeneration of patient-specific ear-shaped cartilage and its first clinical application for auricular reconstruction[J]. EBioMedicine, 2018, 28: 287-302. doi:10.1016/j.ebiom. 2018.01.011.
[12] 吴昆旻, 吴建, 李泽卿, 等. 3D打印辅助上颌骨切除术后缺损重建[J]. 山东大学耳鼻喉眼学报, 2016, 30(6): 29-32, 36. doi:10.6040/j.issn.1673-3770.0.2016.368. WU Kunmin, WU Jian, LI Zeqing, et al. Application of three-dimensional printing technique in assisting reconstruction after maxillectomy[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2016, 30(6): 29-32, 36. doi:10.6040/j.issn.1673-3770.0.2016.368.
[13] 张海, 刘钢, 佟小光, 等. 3D打印技术在复杂鼻颅底肿瘤手术中的应用[J]. 中华耳鼻咽喉头颈外科杂志, 2018, 53(10): 780-784. doi:10.3760/cma.j.issn.1673-0860. 2018.10.012. ZHANG Hai. Application of three-dimensional printing technology in the surgical treatment of nasal skull base tumor[J]. Chinese Journal of Otorhinolaryngology Head and Neck Surgery, 2018, 53(10): 780-784. doi:10.3760/cma.j.issn.1673-0860. 2018.10.012.
[14] Muelleman TJ, Peterson J, Chowdhury NI,et al. Individualized surgical approach planning for petroclival tumors using a 3D printer[J]. J Neurol Surg B Skull Base. 2016,77(3):243-248. doi: 10.1055/s-0035-1566253.
[15] Grau S, Kellermann S, Faust M, et al. Repair of cerebrospinal fluid leakage using a transfrontal, radial adipofascial flap: an individual approach supported by three-dimensional printing for surgical planning[J]. World Neurosurg. 2018,110:315-318. doi: 10.1016/j.wneu. 2017.11.083.
[16] Han B, Liu YJ, Zhang XQ, et al. Three-dimensional printing as an aid to airway evaluation after tracheotomy in a patient with laryngeal carcinoma[J]. BMC Anesthesiol, 2016, 16: 6. doi:10.1186/s12871-015-0170-1.
[17] Mukherjee P, Cheng K, Flanagan S, et al. Utility of 3D printed temporal bones in pre-surgical planning for complex BoneBridge cases[J]. Eur Arch Otorhinolaryngol, 2017, 274(8): 3021-3028. doi:10.1007/s00405-017-4618-4.
[18] 郭颖媛, 张德军, 管国芳, 等. 3D打印技术在耳鼻喉科住院医师规范化培训中的应用探索[J]. 山东大学耳鼻喉眼学报, 2017, 31(3): 119-122. doi:10.6040/j.issn.1673-3770.0. 2017.166. GUO Yingyuan, ZHANG Dejun, GUAN Guofang, et al. Exploration of the application of three-dimensional printing technology in the standardized training of doctors in the otolaryngological department[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2017, 31(3): 119-122. doi:10.6040/j.issn.1673-3770.0. 2017.166.
[19] Rose AS, Kimbell JS, Webster CE, et al. Multi-material 3D models for temporal bone surgical simulation[J]. Ann Otol Rhinol Laryngol, 2015, 124(7): 528-536. doi:10.1177/0003489415570937.
[20] Hochman JB, Rhodes C, Wong D, et al. Comparison of cadaveric and isomorphic three-dimensional printed models in temporal bone education[J]. Laryngoscope, 2015, 125(10): 2353-2357. doi:10.1002/lary. 24919.
[21] Suzuki R, Taniguchi N, Uchida F, et al. Transparent model of temporal bone and vestibulocochlear organ made by 3D printing[J]. Anat Sci Int, 2018, 93(1): 154-159. doi:10.1007/s12565-017-0417-7.
[22] Ahmed S, VanKoevering KK, Kline S, et al. Middle cranial Fossa approach to repair tegmen defects assisted by three-dimensionally printed temporal bone models[J]. Laryngoscope, 2017, 127(10): 2347-2351. doi:10.1002/lary. 26438.
[23] Haffner M, Quinn A, Hsieh TY, et al. Optimization of 3D print material for the recreation of patient-specific temporal bone models[J]. Ann Otol Rhinol Laryngol, 2018, 127(5): 338-343. doi:10.1177/0003489418764987.
[24] Cote V, Schwartz M, Arbouin Vargas JF, et al. 3-Dimensional printed haptic simulation model to teach incomplete cleft palate surgery in an international setting[J]. Int J Pediatr Otorhinolaryngol, 2018, 113: 292-297. doi:10.1016/j.ijporl. 2018.08.016.
[25] Barber SR, Jain S, Son YJ, et al. Virtual functional endoscopic sinus surgery simulation with 3D-printed models for mixed-reality nasal endoscopy[J]. Otolaryngol Head Neck Surg, 2018, 159(5): 933-937. doi:10.1177/0194599818797586.
[26] Hsieh TY, Cervenka B, Dedhia R, et al. Assessment of a patient-specific, 3-dimensionally printed endoscopic sinus and skull base surgical model[J]. JAMA Otolaryngol Head Neck Surg, 2018, 144(7): 574-579. doi:10.1001/jamaoto. 2018.0473.
[27] Hochman JB, Rhodes C, Wong D, et al. Comparison of cadaveric and isomorphic three-dimensional printed models in temporal bone education[J]. Laryngoscope, 2015, 125(10): 2353-2357. doi:10.1002/lary. 24919.
[28] Da Cruz MJ, Francis HW. Face and content validation of a novel three-dimensional printed temporal bone for surgical skills development[J]. J Laryngol Otol, 2015, 129(Suppl 3): S23-S29. doi:10.1017/S0022215115001346.
[29] Berens AM, Newman S, Bhrany AD, et al. Computer-aided design and 3D printing to produce a costal cartilage model for simulation of auricular reconstruction[J]. Otolaryngol Head Neck Surg, 2016, 155(2): 356-359. doi:10.1177/0194599816639586.
[30] Zopf DA, Mitsak AG, Flanagan CL, et al. Computer aided-designed, 3-dimensionally printed porous tissue bioscaffolds for craniofacial soft tissue reconstruction[J]. Otolaryngol Head Neck Surg, 2015, 152(1): 57-62. doi:10.1177/0194599814552065.
[31] Lee VK, Dai GH. Printing of three-dimensional tissue analogs for regenerative medicine[J]. Ann Biomed Eng, 2017, 45(1): 115-131. doi:10.1007/s10439-016-1613-7.
[32] Zhong NP, Zhao X. 3D printing for clinical application in otorhinolaryngology[J]. Eur Arch Otorhinolaryngol, 2017, 274(12): 4079-4089. doi:10.1007/s00405-017-4743-0.
[33] Townsend JM, Ott LM, Salash JR, et al. Reinforced electrospun polycaprolactone nanofibers for tracheal repair in an in vivo ovine model[J]. Tissue Eng Part A, 2018, 24(17/18): 1301-1308. doi:10.1089/ten.TEA. 2017.0437.
[1] WANG Di, CHENG Jinzhang,YU Dan. Application of artificial intelligence based on machine learning in clinical diagnosis and treatment in otolaryngology [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(6): 125-131.
[2] Huimin LIANG,Liqin WANG,Wenjin WAN,Sailei SHI,Jing YUAN,Yujie SHEN,Jiacheng ZHANG,Zefan MAO,Jingzi NI,Yiwen PAN,Zhibin CHEN,Lei CHENG. COVID-19 prevention and control scheme in an ENT endoscopy unit in China [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(2): 88-92.
[3] Zhenhua JIANG,Lijun ZHANG,Ying LI,Yanqin XIAO,Chao LI,Bo SHI,Guiying ZHANG,Bin XU,Wei DENG,Gang LUO,Jifang LUO,Guoqi LIU. Epidemic control practices of an otolaryngology-head and neck surgery ward in an area with non-high incidence of COVID-19 [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(2): 93-98.
[4] ZHU Zhiling, LI SongOverview,GUAN GuofangGuidance. Application and prospect of artificial intelligence in otolaryngology [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(2): 115-120.
[5] Min YIN,Yawen SHI,Xinjie ZHU,Zhibin CHEN,Xi CHEN,Lei CHENG. PBL teaching and the standardization training of residents in otolaryngology-head and neck surgery [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(3): 154-156.
[6] WU Xifu, ZHANG Gehua. Assessment of the effectiveness of problem-based learning during the probation period of the otolaryngology head and [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(4): 116-118.
[7] LI Chao, YAN Yujang, ZHANG Qinyue, CHEN Xia, CAO Yonghua. The application of standardized patients in case-based learning of otolaryngology. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(5): 111-114.
[8] GUO Yingyuan, ZHANG Dejun, GUAN Guofang, WEN Lianji, ZHANG Hui, YU Duojiao, MA Shuaishuai. Exploration of the application of three-dimensional printing technology in the standardized training of doctors in the otolaryngological department. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(3): 119-122.
[9] YANG Jingpu, ZHANG Dejun, ZHAO Yin, CHENG Jinzhang, ZHAO Xue, LIU Yan, YU Dan, WANG Haitao, WEN Lianji. Construction and application of the teaching case database of otolaryngology head and neck surgery. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(6): 98-100.
[10] CHEN Xiumei, SONG Xicheng. Diagnosis and treatment of cervical necrotizing fasciitis: a report of 7 cases and literature review. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(3): 65-67.
[11] CHEN Yanli, ZHU Zhongshou, SONG Peng. The clinical efficacy of suction electro-coagulator under electronic laryngoscopy for treatment of 37 cases of epiglottic cyst [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(5): 92-93.
[12] LIN Junwu, LI Houjie, QU Qian, CHEN Kun. A Example of Giant Parapharyngeal space Osteoma and Literature Review [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(5): 96-96.
[13] WANG Xin, LIANG Guiling. Clinical analysis of 56 cases of throat fungal infection. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(4): 60-61.
[14] WANG Bao-xin, DONG Pin, XIE Fang, DING Jian, SHEN Bin. Surgical treatment of 46 cervical neurilemmoma [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(4): 65-66.
[15] CHEN Fu-quan, LU Lian-jun, CHEN Yang, SHI Zhao-hui. Application of CBL and elicitation teaching mode in teaching of otolaryngology-head and neck surgery for undergraduates [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(4): 90-91.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2006, 20(1): 84 -87 .
[2] NIU Shanli,CHAI Maowen,LI Zhenxiu . Endoscopic rhinoplasty of inferior turbinate in 60 patients with chronic hypertrophic rhinitis[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2006, 20(1): 16 -18 .
[3] MENG Qing-guo,LU Yong-tian,FAN Xian-liang .

Association of killer cell immunoglobulin-like receptor gene polymorphisms with nasopharyngeal carcinoma

[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 196 -199 .
[4] . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 199 -199 .
[5] WAN Li-jia,LU Hai-tao,JIANG Yi-dao,LIU Hui,LI Qin,SHE La-zhi . Effect of H-uvulopalatopharyngoplasty on obstructive sleep apnea
hypopnea syndrome[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 204 -205 .
[6] . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 222 -224 .
[7] JI Xiao-bin,DENG Jia-de,ZANG Lin-quan,WANG Lei,XIE Jun . Blood histamine in guinea pigs with allergic rhinitis[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 228 -230 .
[8] XIANG Deng,LU Yong-tian,SUN Huan-ji . Endoscopic repair for cerebrospinal fluid rhinorrhea in 19 cases and a literature review [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 234 -236 .
[9] . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 253 -257 .
[10]
YIN Guo-hua,ZHONG Xiao . Long-term effect of laser reduction on lingua adenoids
[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 280 -282 .
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd