Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2020, Vol. 34 ›› Issue (5): 157-162.doi: 10.6040/j.issn.1673-3770.0.2019.545

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Diagnosis and treatment of choroidal neovascularization in pathologic myopia

  

  • Received:2019-10-30 Published:2020-11-17

Abstract: Pathologic myopia(PM)is a major cause of vision loss worldwide, particularly in Asian countries. Choroidal neovascularization(CNV)is a severe complication of PM, which can cause macular disorders, leading to central scotoma, metamorphopsia, visual field loss, and finally blindness if not treated. The advents of optical coherence topography(OCT), OCT angiography, and fundus fluorescein angiography are helpful in diagnosing CNV due to PM, which can show the position and size of CNV, whether active or passive. For the treatment, photodynamic and anti-vascular endothelial growth factor(anti-VEGF)therapies are widely applied. In recent years, administering the intravitreal anti-VEGF injection has become the first-line treatment for CNV secondary to PM. Many clinical studies have indicated that intravitreal anti-VEGF injections affect antagonizing neovascularization and reduce macular edema, thereby contributing to visual improvements and better long-term outcomes. This article provides an overview of the current diagnosis and treatment options for myopic CNV.

Key words: Pathologic myopia, Choroidal neovascularization, Diagnosis and treatment

CLC Number: 

  • R774
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