JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2016, Vol. 30 ›› Issue (2): 36-39.doi: 10.6040/j.issn.1673-3770.1.2016.10

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Treatment advance of secondary hyperthyroidism.

CHEN Jun, WANG Jiadong   

  1. Department of Otolaryngology, Renji Hospital Shanghai Jiaotong University School of Medicine, Shanghai 200001, China
  • Received:2016-03-10 Online:2016-04-16 Published:2016-04-16

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Abstract: Secondary hyperparathyroidism(SHPT)is a common complication of metabolic disorders in chronic kidney disease(CKD)patients. The Incidence of SHPT has increased with the passing years and the clinical manifestations are increased parathyroid hormone level, calcium-phosphorus metabolic disorders and bone pain, et al. In addition to the familiar factors, such as serum calcium and phosphorus, vitamin D and its receptor, calcium-sensing receptors, the mechanism for CKD-SHPT also includes the molecular and cellular mechanism, such as peptidyl-prolyl cis-trans isomerase 1(Pin1), Klotho protein and fibroblast growth factor-23(FGF23). Nowadays, the therapeutic strategy is mainly focused on medication, surgery and interventional therapy. This review will also introduce the pre-operation localization methods and surgical methods. Its critical to choose the suitable surgical methods for SHPT treatment.

Key words: Localization, Secondary hyperparathyroidism, Treatment

CLC Number: 

  • R582.2
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