Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2019, Vol. 33 ›› Issue (1): 77-80.doi: 10.6040/j.issn.1673-3770.1.2018.031

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Correlation between PM2.5 and upper airway resistance in patients with allergic rhinitis

JIN Xing1, HU Dayu2, ZHU Li1, DENG Furong2, LIU Junxiu1   

  1. School of Public Health, Peking University Health Science Center, Beijing 100191, China
  • Online:2019-01-20 Published:2019-01-28

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Abstract: Objective To investigate the relationship between upper airway resistance and the concentration of atmospheric particulate matter with diameter <2.5 micrometers(PM2.5)in patients with allergic rhinitis(AR). Methods Sixty patients with clinically diagnosed AR were randomly selected for nasal acoustic reflex and nasal resistance measurement. The PM2.5 concentration in their living areas was continuously monitored. Using SPSS 20.0 statistical software, multiple linear regression models were used. The patient's total nasal resistance, nasal volume, and nasal minimum cross-sectional area were correlated with the air pollution exposure levels. The level of significance was set at P<0.05. Results Nasal acoustic reflex and nasal resistance measurements showed that the total nasal resistance, nasal minimum cross-sectional area, and nasal volume of the subject varied dynamically with varying PM2.5 concentration, and the difference was statistically significant. Conclusion The concentration of PM2.5 affects the upper airway resistance of patients with AR. The greater the concentration of PM2.5 and longer the exposure time, the greater the upper airway resistance of patients with AR.

Key words: Allergic rhinitis, Fine particulate matter, Upper airway resistance, Nasal acoustic reflex, Nasal resistance measurement

CLC Number: 

  • R765.2
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