伴发梅尼埃病的良性阵发性位置性眩晕的临床特点

doi:10.6040/j.issn.1673-3770.1.2019.024

Abstract

Abstract: Objective

To study the clinical characteristics and treatment outcomes of patients with benign paroxysmal positional vertigo (BPPV) associated with Meniere′s disease (MD).

Method

A total of 256 patients with BPPV were enrolled in the study, of which 32 patients with secondary BPPV were excluded. Out of the remaining 224 patients, 28 patients having BPPV associated with MD were included in the trial group and 196 patients with no adjunctive problem associated with BPPV (idiopathic) were included in the control group. All the patients were diagnosed using the Dix-Hallpike positional test and were treated with canalith repositioning procedure (CRP). The age, sex, site of involvement, type of BPPV, duration of symptoms, and treatment outcomes were compared.

Results

The clinical manifestations of BPPV were seen more commonly among the females in the trial group. (P<0.05). Involvement of the lateral canal of the ear was more common in patients in the trial group (P<0.001). There was no statistical difference in the average age and in right and left ear involvement between groups. BPPV was ipsilateral to the ear with MD in 75% of patients and MD was present before the diagnosis of BPPV in all patients. Comparative analyses of the cure rate of both groups after 1 day, 1 week, and 1 month were significant (P<0.01, P<0.05, P<0.05 respectively).

Conclusion

The clinical features and therapeutic outcomes of MD-associated BPPV differ from those of idiopathic BPPV. MD-associated BPPV was found to be more frequent in females and the lateral canal involvement was higher in most patients. Patients were already affected by MD before the development of BPPV. This disease may follow a different clinical course and respond less effectively to CRP treatment.

Key words: Meniere′s disease, Benign paroxysmal positional vertigo, Canalith repositioning procedure, Positional test, Treatment outcome

CLC Number:

R764

Dengyuan WANG,Zhibin CHEN,Miaolin WANG. An assessment of the clinical features of benign paroxysmal positional vertigo associated with Meniere' s disease[J].Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(3): 61-65.

Figures/Tables 1

Table 1

Comparative analysis of clinical characteristics of patients with idiopathic BPPV and BPPV associated MD"

指标	试验组（n=28）	对照组（n=196）	χ^２/ t	P
性别			4.644	0.031
男	5	76
女	23	120
年龄（ $x ˉ ± s$ ，岁）	45.3±7.9 （30~60）	42.1±8.5 （26~76）	1.968	0.057
BPPV病程（ $x ˉ ± s,$ d）	53.2±11.7	41.2±10.8	5.45	0.000
BPPV侧别			0.127	0.721
左侧	13	84
右侧	15	112
受累半规管
后半规管	13	127	3.527	0.060
外半规管	15	27	25.469	0.000
上半规管		13
多半规管		29

Table 1

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An assessment of the clinical features of benign paroxysmal positional vertigo associated with Meniere' s disease

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