JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2016, Vol. 30 ›› Issue (6): 85-89.doi: 10.6040/j.issn.16733770.0.2016.213

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Laryngopharyngeal reflux and otorhinolaryngology diseases

SUN Na, CHEN Xiaoping   

  1. Department of Otolaryngology, Gongli Hospital, Second Military Medical University, Shanghai 200135, China
  • Online:2016-12-16 Published:2016-12-16

Abstract: Laryngopharyngeal reflux is one of the major causes of respiratory symptoms related to pharyngeal foreign body sensation, hoarseness and other symptoms of the upper respiratory tract. It is becoming a hotspot of otolaryngologists. At present, there are still a lot of controversies about the diagnosis and treatment of laryngopharyngeal diseases, such as sinusitis, otitis media, sleep apnea hypopnea syndrome, and so on. Now experts on throat diseases are working on a standardized diagnosis, treatment and efficacy evaluation system and carrying out multicenter clinical researches, in order to normalize the diagnosis and treatment of laryngopharyngeal reflux.

Key words: Hoarseness, Nasosinusitis, Otitis media, Pharyngeal foreign body sensation, Laryngopharyngeal reflux, Obstructive sleep apnea hypopnea syndrome

CLC Number: 

  • R766
[1] Adams J, Heintz P, Gross N, et al. Acid/pepsin promotion of carcinogenesis in the hamster cheek pouch[J]. Arch Otolaryngol Head Neck Surg, 2000, 126(3):405409.
[2] Wright M R, Sharda R, Vaezi M F, et al. Unmet needs in treating laryngopharyngeal reflux disease: where do we go from here?[J]. Expert Rev Gastroenterol Hepatol, 2016, 10(9):9951004.
[3] Lechien J R, Delvaux V, Huet K, et al. Phonetic approaches of laryngopharyngeal reflux disease: a prospective study[J]. J Voice, 2016, pii: S08921997(16)000618.
[4] Fisichella P M. Hoarseness and laryngopharyngeal reflux[J]. JAMA, 2015, 313(18):18531854
[5] Belafsky P C, Postma G N, Koufman J A. Laryngopharyngeal reflux symptoms improve before changes in physical findings[J]. Laryngoscope, 2001, 111(6):979981.
[6] 李进让. 咽喉反流性疾病规范化诊断和治疗[J].中国耳鼻咽喉头颈外科, 2015, 22(9):435437.
LI Jinrang. Standardization of diagnosis and treatment for laryngopharyngeal reflux disease[J]. Chin Otolaryngol Otolaryngol Head Neck Surg, 2015, 22(9):435437.
[7] 李进让, 肖水芳, 李湘平, 等. 咽喉反流性疾病诊断与治疗专家共识(2015年)解读[J]. 中华耳鼻咽喉头颈外科杂志, 2016, 51(5):327332.
LI Jinrang, XIAO Shuifang, LI Xiangping, et al. Interpretation of expert consensus of diagnosis and treatment for laryngopharyngeal reflux disease(2015)[J]. Chin J Otorhinolarynol Head Neck Surg, 2016, 51(5):327332.
[8] 闫燕, 万苡辰, 刘庆松, 等. 两种方法诊断咽喉反流患者的嗓音特征及治疗前后变化[J]. 中国耳鼻咽喉头颈外科, 2015, 22(9):442444.
YAN Yan, WAN Yichen, LIU Qingsong, et al. Voice characteristics and changes before and after treatment of ryngopharyngeal reflux patients diagnosed by two diagnostic methods[J]. Chin Otolaryngol Otolaryngol Head Neck Surg, 2015, 22(9):442444.
[9] 李进让, 肖水芳, 李湘平, 等. 咽喉反流性疾病诊断与治疗专家共识(2015年)[J]. 中华耳鼻咽喉头颈外科杂志, 2016, 51(5):324326.
LI Jinrang, XIAO Shuifang, LI Xiangping, et al. Expert consensus of diagnosis and treatment for laryngopharyngeal reflux disease (2015)[J]. Chin J Otorhinolarynol Head Neck Surg, 2016, 51(5):324326.
[10]Ocak E, Kubat G, Yorulmaz I[DD(-*3]·[DD)]. Immunoserologic pepsin detection in the saliva as a noninvasive rapid diagnostic test for laryngopharyngeal reflux[J]. Balkan Med J, 2015, 32(1):4650.
[11] SeregBahar M, Jerin A, Jansa R, et al. Pepsin and bile acids in saliva in patients with laryngopharyngeal refluxa prospective comparative study[J]. Clin Otolaryngol, 2015, 40(3):234239.
[12] Spyridoulias A, Li llie S, Vyas A, et al. Detecting laryngopharyngeal reflux in patients with upper airways symptoms: Symptoms, signs or salivary pepsin?[J]. Respir Med, 2015, 109(8):963969.
[13] Sataloff R T, Hawkshaw M J, 徐文. 喉咽反流性疾病[J]. 中华耳鼻咽喉头颈外科杂志, 2014, 49(5):432436.
Sataloff R T, Hawkshaw M J, XU Wen. Laryngopharyngeal reflux disease[J]. Chin J Otorhinolarynol Head Neck Surg, 2014, 49(5):432436.
[14] Cherry J, Margulies S I. Contact ulcer of the larynx[J]. Laryngoscope, 1968, 78(11):19371940.
[15] Koufman J A. The otolaryngologic manifestations of gastroesophageal reflux disease(GERD): a clinical investigation of 225 patients using ambulatory 24hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury[J]. Laryngoscope, 1991, 101(4 pt 2 Suppl 53):178.
[16] Koufman J A, Blalock P D. Functional voice disorders[J]. Otolaryngol Clin North Am, 1991, 24(5):10591073.
[17] 吴彦桥, 梁芳芳. 喉咽反流性鼻炎的临床初步研究[J]. 临床耳鼻咽喉头颈外科杂志, 2016, 30(3):200202.
WU Yanqiao, LIANG Fangfang. Clinical pilot study on the rhinitis due to laryngopharyngeal reflux[J]. J Clin Otorhinolaryngol Head Neck Surg, 2016, 30(3):200202.
[18] Luo H N, Yang Q M, Sheng Y, et al. Role of pepsin and pepsinogen: linking laryngopharyngeal reflux with otitis media with effusion in children[J]. Laryngoscope, 2014, 124(7):294300.
[19] Gilani S, Quan S F, Pynnonen M A, et al. Obstructive Sleep Apnea and Gastroesophageal Reflux: A Multivariate PopulationLevel Analysis[J].Otolaryngol Head Neck Surg, 2016, 154(2):390395.
[20] Erylmaz A, Erien L, Demir U L, et al. Management of patients with coexisting obstructive sleep apnea and laryngopharyngeal reflux disease[J]. Eur Arch Otorhinolaryngol, 2012, 269(12):25752580.
[21] Friedman M, Wilson M N, Pulver T M, et al. Measurements of adult lingual tonsil tissue in health and disease[J]. Otolaryngol Head Neck Surg, 2010, 142(4):520525.
[22] Rodrigues M M, Dibbern R S, Santos V J, et al. Influence of obesity on the correlation between laryngopharyngeal reflux and obstructive sleep apnea[J]. Braz J Otorhinolaryngol, 2014, 80(1):510.
[23] Dua K, Surapaneni S N, Kuribayashi S, et al. Protectiveroleof aerodigestive reflexes against aspiration: study on subjects with impaired and preserved reflexes[J]. Gastroenterology, 201l, 140(7):19271933.
[24] Senior B A, Khan M, Sehwimmer C, et al. Gastroesophageal reflux and obstructive sleep apnea[J]. Laryngoscope, 2001, 111(12):21442146.
[25] 柴小花, 张宁, 许艳芳, 等. 质子泵抑制剂在阻塞性睡眠呼吸暂停低通气综合征伴咽喉反流者中的应用[J]. 中国耳鼻咽喉颅底外科杂志, 2012, 18(3): 179182.
CHAI Xiaohua, ZHANG Ning, XU Yanfang, et al. Application of proton pump inhibitor in patients with obstructive sleep apnea and laryngopharyngeal reflux[J]. Chin J Otorhinolaryngol Skull Base Surg, 2012, 18(3):179182.
[26] Lechien J R, Finck C, Costa de Araujo P, et al. Voice outcomes of laryngopharyngeal reflux treatment: a systematic review of 1483 patients[J]. Eur Arch Otorhinolaryngol, 2016, 23.
[27] De Bortoli N, Martinucci I, Bertani L, et al. Esophageal testing: what we have so far[J]. World J Gastrointest Pathophysiol, 2016, 7(1):7285.
[28]王宇光, 张立红, 余力生, 等. 咽喉反流对嗓音疾病患者生活质量影响的临床研究[J]. 中华耳鼻咽喉头颈外科杂志, 2015, 50(12): 973977.
WANG Yuguang, ZHANG Lihong, YU Lisheng, et al. Clinical study of the influence of laryngopharyngeal reflux on quality of life in patients with dysphonia[J]. Chin J Otorhinolarynol Head Neck Surg, 2015, 50(12):973977.
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