%A CHE Juan, ZHAO Hongchun, LI Jinling, WANG Yanfei
%T The relationship between D-Dimer and nasopharyngeal carcinoma
%0 Journal Article
%D 2015
%J Journal of Otolaryngology and Ophthalmology of Shandong University
%R 10.6040/j.issn.1673-3770.0.2015.150
%P 47-49
%V 29
%N 5
%U {http://ebhyxbwk.njournal.sdu.edu.cn/CN/abstract/article_1862.shtml}
%8 2015-10-16
%X Objective To investigate the prognostic value of plasma D-dimer for nasopharyngeal carcinoma. Method Sixty-nine nasopharyngeal carcinoma patients and their gender-and age-matched healthy individuals were prospectively enrolled, and their plasma D-Dimer on admission were compared. The association between plasma D-Dimer and clinical stage of nasopharyngeal carcinoma was analyzed. The prognostic value of D-dimer for all-cause mortality was estimated by receiver operating characteristic (ROC) curves and Kaplan-Meier approach. Results Compared with healthy individuals, nasopharyngeal patients had significantly higher plasma D-dimer. Plasma D-Dimer increased as the advance of clinical stage of nasopharyngeal carcinoma. The area under ROC curve of plasma D-Dimer for all-cause mortality was 0.72. Patients with increased D-Dimer (more than 0.55 mg/L) have higher risk of death than the patients with normal D-Dimer (less than 0.55 mg/L). Conclusion D-Dimer is a useful prognostic factor for nasopharyngeal carcinoma. Increased D-Dimer is associated with poor prognosis.