%A LI Bin, FANG Xuejun, WU De, HUANG Min
%T Agreement study of implantable collamer lens based on NK and KS formulas in the early stage after surgery
%0 Journal Article
%D 2021
%J Journal of Otolaryngology and Ophthalmology of Shandong University
%R 10.6040/j.issn.1673-3770.0.2021.346
%P 33-41
%V 35
%N 6
%U {http://ebhyxbwk.njournal.sdu.edu.cn/CN/abstract/article_2912.shtml}
%8
%X **Objective** To investigate the agreement of NK and KS formulas based on CASIA OCT in predicting the vault after implantation of an implantable collamer lens(ICL). **Methods** This prospective case study included 25 patients(50 eyes)with moderate to high myopia undergoing ICL implantation. CASIA OCT was used to analyze the vault change at one day, one week, and one month after surgery, and the difference and agreement between the vault predicted by the NK and KS formulas and the actual vault postoperatively. Variation of the vault at each follow-up was analyzed using One-way Repeated Measures Anova. NK and KS formulas were used to predict the vault and vault differences at different time points. A paired t-test was used to analyze the difference between the actual vault after surgery at each follow-up and the vault predicted by the NK/KS formulas. The agreement between the actual vault after surgery at each follow-up and the vault predicted by the NK/KS formulas were analyzed using Bland-Altman analysis. Multiple linear regression was used to analyze the relationship between the vault and the preoperative parameters of the anterior segment. **Results** The vault decreased with time in the early stage after surgery. The difference of the vault at one day and one week was(122.22±81.03)μm(*P*<0.05), at one day and one month after the operation was(169.04±84.20)μm(*P*<0.05), and at one week and one month after the operation was(46.83±45.70)μm(*P*<0.05). There was a statistical difference between the predicted value of the NK formula and the actual vault measured one day after the operation(*P*<0.05). There was a statistically significant difference between the predicted vault value of the KS formula and the actual vault measured one day and one month after surgery(*P*<0.05). The agreement between the actual vault after surgery at one week and the vault predicted by the NK/KS formulas was the highest. The postoperative vault was correlated with the anterior chamber width, crystalline lens rise, and angle to angle distance. The consistency between the vault prediction value of the NK formula and the first day after the operation was lower than the KS formula but higher than the KS formula in terms of one week and one month. **Conclusion** The vault decreased with time during the early postoperative period. The predicted vault of the two prediction formulas of CASIA OCT was the most consistent with the vault at one week after surgery. The NK formula could accurately predict the actual value of the postoperative vault. Furthermore, the NK formula is better than the KS formula in predicting the postoperative vault at early stage.