TLR通路基因多态性与变应性鼻炎的关联研究
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陈若希,张清照,陆美萍,朱歆洁,程雷
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Association of Toll-like receptor pathway gene polymorphisms with allergic rhinitis
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Ruoxi CHEN,Qingzhao ZHANG,Meiping LU,Xinjie ZHU,Lei CHENG
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表2 病例组和对照组研究对象的临床特征
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Table 2 Distribution of selected variables between cases and controls
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| 变量 | 病例组 (n = 452) | 对照组 (n = 495) | P | | 年龄 (岁, ) | 19.70 ± 12.60 | 20.10 ± 12.61 | 0.597a | | 性别[n(%)] | | | | 男 | 302(66.8) | 303(61.2) | 0.073a | | 女 | 150(33.2) | 192(38.8) | | | 鼻炎病程 (年, ) | 6.62 ± 5.87 | | | | 鼻腔总症状 ( ) | 5.25 ± 2.39 | | | | 血清总IgE [kU/L, M (IQR)] | 264.0 (120.6~593.5) | 26.8 (11.1~52.2) | < 0.001b | | 特异性IgE [kUA/L, M (IQR)] | | | | | 屋尘螨 | 29.0(4.6~72.5) | — | | | 粉尘螨 | 24.1 (5.0~69.9) | — | | | ECP [μg/L, median(IQR)] | 12.7 (5.2~28.7) | 4.6 (3.1~7.5) | < 0.001b | | 伴随哮喘 | | | | | 是 | 118（26.1） | | | | 否 | 271（60.0） | | | | 家族史 | | | | | 是 | 122（27.0） | | | | 否 | 269（59.5） | | |
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