J Otolaryngol Ophthalmol Shandong Univ ›› 2017, Vol. 31 ›› Issue (2): 116-120.doi: 10.6040/j.issn.1673-3770.0.2016.293

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Advances in clinical diagnosis and treatment of sinonasal mucosal malignant melanoma.

  

  1. 1. Bengbu Medical College, Bengbu 233030, Anhui, China;2. Department of Otolaryngology Heck and Neck Surgery, The First Affiliated Hospital of Bengbu Medical University, Bengbu 233004, Anhui, China
  • Received:2016-06-29 Online:2017-04-16 Published:2017-04-16

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Abstract: Sinonasal mucosal malignant melanoma(SMMM)is a rare sinonasal malignant tumor. Due to the atypical symptoms, most patients were diagnosed as the advanced stage, and the 5-year survival rate is limited to 20%-30%. Pathology is the gold standard for diagnosis. Black pigment particles found in the tissue cells can help the diagnosis; for the non-pigmented melanoma, immunohistochemistry can help to identify the diagnosis. Compared with Ballantyne staging, the 7th edition of American Joint Committee on Cancer(AJCC)malignant melanoma tumor node metastasis(mmTNM)staging may be more suitable for SMMM. At present, the surgical treatment is the first choice for early SMMM, and a comprehensive treatment method, such as surgery combined with radiotherapy and biochemotherapy is favorable to improving the survival rate of patients.

Key words: Malignant melanoma, Diagnosis, Sinonasal, Neoplasms staging, Therapy

CLC Number: 

  • R739.62
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