JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2008, Vol. 22 ›› Issue (6): 525-527.

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Clinical value of serum squamous cell carcinoma antigen in nasal inverted papilloma

 HAN Zhen-Qiang, WANG Jian-Guo   

  1. Department of Otorhinolaryngology ＆ Head and Neck Surgery, Xingtai Hospital of Ophthalmology, Xingtai 054001, Hebei, China
  • Received:2008-08-01 Revised:2088-12-02 Online:2008-12-16 Published:2008-12-16

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Abstract:

To investigate the significance of the serum level of squamous cell carcinoma antigen（SCCAg） in nasal inverted papilloma（NIP）. MethodsThe serum SCCAg levels were determined by microparticle enzymeimmunoassay(MEIA) in 34 patients with NIP and 12 patients with nasal squamous cell carcinoma (NSCC) before and after the operations. ResultsThe positive rate of squamous cell carcinoma antigen in 34 patients with NIP was 67.64% (23/34) and in 12 patients with NSCC it was 75%(9/12). The postoperative serum level of SCCAg had a statistical significance compared to that before the operations(P<0.05). The serum SCCAg levels in patients with recurrence significantly increased half a year later. ConclusionThe SCCAg level plays an important role in evaluating the biological characteristics, therapeutic effects and  prognosis in patients with NIP.

Key words:  Papilloma, inverted; Microparticle enzyme immunoassay; Squamous cell carcinoma antigen; Prognosis

CLC Number: 

  • R739.65
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