Abstract:

Objective     To evaluate the correlation between visual outcome and foveal photoreceptor integrity after treatment of eyes with chronic central serous chorioretinophy(CSC). Methods    The medical records of 30 patients (30 eyes) with chronic CSC who were treated with verteporfin photodynamic therapy (PDT) were retrospectively studied. Using spectraldomain optical coherence tomography, the status of the inner segment and outer segment photoreceptor junction (IS/OS) was assessed as a hallmark of the integrity of the foveal photoreceptor layer. Results      At the finial visit, 26(86.7%) eyes had stable or improved vision. A complete or discontinuous IS/OS line was detected beneath the fovea in 20 (66.7%) and 6 (20.0%) eyes, respectively, whereas 2 (6.7%) eyes had no IS/OS line. Eyes with a continuous or discontinuous IS/OS line had better final visual acuity than eyes without an IS/OS line. Conclusion      Integrity of the photoreceptor layer beneath the fovea is associated with the final visual acuity in chronic CSC after PDT.

Key words: Central serous chorioretinophy; Spectral-domain optical coherence tomography; Photoreceptor layer