Abstract: Objective To study and analyze the test results used for the detection of HBsAg, anti-HCV, anti-Treponema pallidum antibody(anti-TP)and anti-HIV in patients, prior to refractive surgery and to standardize the surgical management. Methods Enzyme-linked immunosorbent assay was used to detect four different indicators of infection in 4630 patients and the results were analyd retrospectively. Results The observed total positive rate, in the 4630 patients involved in the study, was 3.02% (n=140). The positive rates observed for HBsAg, anti-TP, anti-HCV, and anti-HIV were 2.13% (n=99), 0.62% (n=29), 0.19% (n=9), and 0.06% (n=3), respectively. In the present study, the total positive rate and the positive rates for HBsAg and anti-HIV were observed to be higher in male patients, compared to female patients (χ2 was 8.04, 16.11 and 6.05, respectively, P<0.01). Conclusions Detection of infection indicators, prior to laser corneal refractive surgery, can aid in understanding the infection status of patients, which helps in decreasing the risk of infection and enhances the safe implementation of the surgical procedure.

Key words: Laser corneal refraction surgery, Infection indicators, H hepatitis B surface antigen, Antibody to hepatitis C virus, Anti-Treponema pallidum antibody, human immunodeficiency virus