JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2016, Vol. 30 ›› Issue (1): 14-16.doi: 10.6040/j.issn.1673-3770.0.2015.328

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Study on measurement of nasal nitric oxide in children with allergic rhinitis.

WANG Guixiang, WANG Pengpeng, TANG Lixing, ZHANG Yamei, ZHANG Jie, GE Wentong.   

  1. Department of Otorhinolaryngolog &Head and Neck surgery, Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, Children's Hospital of Capital Medical University, Beijing 100045, China
  • Received:2015-08-09 Online:2016-02-16 Published:2016-02-16

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Abstract: Objective To investigate the measurement of nasal nitric oxide in children with allergic rhinitis. Methods A total of 50 children(100 cases of nasal cavity)without nasal symptoms were selected as the control group between September 2013 and August 2014. Another 58 children(116 cases of nasal cavity)with allergic rhinitis between September 2013 and August 2014 were recruited as the allergy group. The nasal nitric oxide concentration of children from the two groups was measured by ‘passive nasal respiration’ technology. Results The concentration of nasal nitric oxide in the control group was(266±84)ppb and was(426±151)ppb in the allergy group(P<0.01). There was no significant difference in concentration of nasal nitric oxide between different genders(P>0.05). Conclusion The concentration of nasal nitric oxide may be affected by age and cooperation of children. The passive nasal respiration technology is a user-friendly and noninvasive measurement for initial diagnosis of allergic rhinitis.

Key words: Allergic rhinitis, Exhalation, Nose, Child, Nitric oxide

CLC Number: 

  • R765.21
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