JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2017, Vol. 31 ›› Issue (4): 54-59.doi: 10.6040/j.issn.1673-3770.0.2017.100

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Correlation between obstructive sleep apnea hypopnea syndrome and upper airway measurements of different genders.

LIU Wenjun1, YU Xueying1,2, LÜ Dan1,2, CHEN Zhenggang3, ZHANG Yanqing1,2, MEI Xubin1, YANG Ke1,2   

  1. 1. Department of Otolaryngology, Qingdao Municipal Hospital, Qingdao 266071, Shandong, China;2. Weifang Medical University, Weifang 261042, Shandong, China;3. Department of Stomatology, Qingdao Municipal Hospital, Qingdao 266071, Shandong, China
  • Received:2017-03-06 Online:2017-08-16 Published:2017-08-16

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Abstract: Objective To investigate the ability of upper airway measurement to predict the severity of obstructive sleep apnea hypopnea syndrome(OSAHS)in different genders. Methods This study included 163 OSAHS patients(98 men and 65 women)diagnosed by polysomnography. Computed tomography(CT)scans of the upper airway during quiet breathing were performed. Parameters including the vertical distance from the inferior margin of the hyoid to the inferior mandibular margin(submental point)(D-HM)and from the forefront points of the hyoid to the inferior mandibular margin(submental point)were measured. Results The AHI was 14.2-52.3/h(mean, 36.22±5.64/h)in men and 9.6-46.4/h(mean, 29.38 ± 3.90/h)in women. The LSaO2 was 48%-79%(mean, 63.93%±10.51%)in men and 59%-87%(mean, 70.92%±9.17%)in women. The minimal anteroposterior diameter, left and right diameters, and area of each plane were negatively correlated with the AHI and positively correlated with LSaO2. In men, the AHI and LSaO2 were strongly correlated with the minimal cross-sectional area of the retropalatal area(r=-0.441; P < 0.01); the AHI and LSaO2 of women were strongly correlated with the minimal cross-sectional area of the lingual region(r=-0.403; P<0.01). There was a significant difference in the vertical distance from the inferior margin of 山东大学耳鼻喉眼学报31卷4期 -刘文君,等.不同性别阻塞性睡眠呼吸暂停低通气综合征患者与上气道影像学相关性的研究 \=-the hyoid to the D-HM, and in the distance from the forefront points of the hyoid to the inferior mandibular margin(submental point), between men and women(P<0.01). Some OSAHS patients received modified UPPP surgery. The effective rate in men and women 3 months after surgery was 84.31% and 58.06%, respectively. Significant postoperative differences as measured by CT scan were observed in four male OSAHS patients, but only one female patient. Conclusions CT measurements of the upper airway of OSAHS patients could help predict the severity of OSAHS. This study revealed a significant difference between the upper airway measurements of men and women. Individualized treatments should consider gender as a factor.

Key words: Obstructive sleep apnea hypopnea syndrome, Hyoid, Polysomnography, X-ray computed tomography, Gender, H-uvulopalatopharyngoplasty

CLC Number: 

  • R766.7
[1] 中华医学会耳鼻咽喉头颈外科学分会咽喉学组, 中华耳鼻咽喉头颈外科杂志编辑委员会. 阻塞性睡眠呼吸暂停低通气综合征诊断和外科治疗指南[J]. 中华耳鼻咽喉头颈外科杂志, 2009, 44(2):95-96. Chinese magazine editor committee of otolaryngology head and neck surgery, Chinese medical association otolaryngology head and neck surgery branch of the throat group.Patients with obstructive sleep apnea hypopnea syndrome diagnosis and surgical treatment guidelines[J]. Chin J Otolaryngology Head Neck Surgery, 2009, 44(2): 95-96.
[2] 曹鑫, 叶京英, 张俊波,等. 舌骨位置对预测阻塞性睡眠呼吸暂停低通气综合征腭部手术疗效的作用[J]. 中华耳鼻咽喉头颈外科杂志, 2015, 50(4):281-285. CAO Xin, YE Jingying, ZHANG Junbo, et al. Effects of hyoid position on surgical treatment outcome for patients with obstructive sleep apnea hypopnea syndrome[J]. Chin J Otorhinolarynol Head Neck Surg, 2015, 50(4):281-285.
[3] 顼晋昆, 叶京英, 常青林, 等. 上气道CT软组织测量值与阻塞性睡眠呼吸暂停低通气综合征病情程度的关系[J].中华耳鼻咽喉头颈外科杂志, 2010, 45(5): 387-392. XU Jinkun, YE Jingying, CHANG Qinglin, et al.Correlation between upper airway soft tissue 3-D measurement and the severity of obstructive sleep apnea hypopnea syndrome[J]. Chin J Otorhinolarynol Head Neck Surg, 2010, 45(5):387-392.
[4] 尹国平, 叶京英, 常青林. 阻塞性睡眠呼吸暂停低通气综合征患者咽腔容积测量[J]. 中国耳鼻咽喉头颈外科, 2008, 15(2): 103-106. YIN Guoping, YE Jingying, CHANG Qinglin, et al. Pharyngeal volume measurement using CT three-dimensional reconstruction technique in patients with OSAHS[J]. Chinese Archives of Otolaryngology-Head and Neck Surgery, 2008, 15(2): 103-106.
[5] Deegan PC, McNichols WT. Pathophysiology of obstructive sleep apnea[J]. EurRespir J, 1995, 8(7):1161-1178.
[6] Huang TW, Cheng PW. Microdebrider-assisted Extended Uvulopalatoplasty: an Effective and Safe Technique for Selected Patients with Obstructive Sleep Apnea Syndrome[J]. Arch Otolaryngol Head Neck Sury, 2008, 134(2): 141-145.
[7] 胡芸, 张树桐, 金朝林, 等. 64层螺旋CT诊断阻塞性睡眠呼吸暂停综合征[J]. 放射学实践, 2009, 24(6): 622-624. HU Yun, ZHANG Shutong, JIN Chaolin,et al. Clinical Application of 64-slice Spiral CT in Diagnosis of Obstructive Sleep Apnea Hypopnea Syndrome[J]. Radiologic Practice, 2009, 24(6): 622-624.
[8] 乔晓丞, 李树华, 石洪金. 阻塞性睡眠呼吸暂停低通气综合征患者及正常成人呼吸运动周期中上气道形态变化的研究[J]. 临床耳鼻咽喉头颈外科杂志, 2009, 23(24): 1123-1127. QIAO Xiaocheng, LI Shuhua, SHI Hongjin. Difference of upper airway variety with respiration in the sufferer of OSAHS and normal adult[J]. Journal of Clinical Otorhinolaryngology Head and Neck Surgery, 2009, 23(24): 1123-1127.
[9] Mohsenin V. Effects of gender on upper airway collapsibility and severity of obstructive sleep apnea[J]. Sleep Med, 2003, 4(6): 523-529.
[10] 尹国平, 叶京英, 常青林,等. 中老年女性阻塞性睡眠呼吸暂停低通气综合征患者上气道形态功能研究[J]. 中国耳鼻咽喉头颈外科, 2008, 15(6): 357-360. YIN Guoping, YE Jingying, CHANG Qinglin, et al.Upper airway morphology and function study of middle-age and old women with OSAHS[J]. Chin J Otorhinolarynol Head Neck Surg, 2008, 15(6): 357-360.
[11] 易红良, 殷善开, 关建,等. 颏舌肌前移术的应用解剖学研究[J]. 临床耳鼻咽喉科杂志, 2004, 18(12): 719-722. YI Hongliang, YIN Shankai, GUAN Jian, et al. Applied anatomic study for genioglossusadvancement[J]. Clin J Otorhinolarynol Head Neck Surg, 2004, 18(12): 719-722.
[12] 马国伟, 张庆泉, 周文亮. 舌骨位置与舌后气道最小截面积及阻塞性睡眠呼吸暂停低通气综合征严重程度的相关性分析[J]. 山东大学耳鼻喉眼学报, 2013, 27(6): 66-68. MA Guowei, ZHANG Qingquan, ZHOU Wenliang. Correlation of hyoid position, minimal retroglossal cross-section area and severity of obstructive sleep apnea hypopnea syndrome[J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(6): 66-68.
[13] Leiter JC. Upper airway shape: Is it important in the pathogenesis of obstructive sleep apnea? [J]. Am J RespirCrit Care Med, 1996, 153(3): 894-898.
[14] Millman RP, Carlisle CC, Rosenberg C, et al. Simple predictors of uvulopalatopharyngoplasty outcome in the treatment of obstructive sleep apnea[J]. Chest, 2000, 118(4):1025-1030.
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