JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2017, Vol. 31 ›› Issue (4): 54-59.doi: 10.6040/j.issn.1673-3770.0.2017.100

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Correlation between obstructive sleep apnea hypopnea syndrome and upper airway measurements of different genders.

LIU Wenjun1, YU Xueying1,2, LÜ Dan1,2, CHEN Zhenggang3, ZHANG Yanqing1,2, MEI Xubin1, YANG Ke1,2   

  1. 1. Department of Otolaryngology, Qingdao Municipal Hospital, Qingdao 266071, Shandong, China;2. Weifang Medical University, Weifang 261042, Shandong, China;3. Department of Stomatology, Qingdao Municipal Hospital, Qingdao 266071, Shandong, China
  • Received:2017-03-06 Online:2017-08-16 Published:2017-08-16

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Abstract: Objective To investigate the ability of upper airway measurement to predict the severity of obstructive sleep apnea hypopnea syndrome(OSAHS)in different genders. Methods This study included 163 OSAHS patients(98 men and 65 women)diagnosed by polysomnography. Computed tomography(CT)scans of the upper airway during quiet breathing were performed. Parameters including the vertical distance from the inferior margin of the hyoid to the inferior mandibular margin(submental point)(D-HM)and from the forefront points of the hyoid to the inferior mandibular margin(submental point)were measured. Results The AHI was 14.2-52.3/h(mean, 36.22±5.64/h)in men and 9.6-46.4/h(mean, 29.38 ± 3.90/h)in women. The LSaO2 was 48%-79%(mean, 63.93%±10.51%)in men and 59%-87%(mean, 70.92%±9.17%)in women. The minimal anteroposterior diameter, left and right diameters, and area of each plane were negatively correlated with the AHI and positively correlated with LSaO2. In men, the AHI and LSaO2 were strongly correlated with the minimal cross-sectional area of the retropalatal area(r=-0.441; P < 0.01); the AHI and LSaO2 of women were strongly correlated with the minimal cross-sectional area of the lingual region(r=-0.403; P<0.01). There was a significant difference in the vertical distance from the inferior margin of 山东大学耳鼻喉眼学报31卷4期 -刘文君,等.不同性别阻塞性睡眠呼吸暂停低通气综合征患者与上气道影像学相关性的研究 \=-the hyoid to the D-HM, and in the distance from the forefront points of the hyoid to the inferior mandibular margin(submental point), between men and women(P<0.01). Some OSAHS patients received modified UPPP surgery. The effective rate in men and women 3 months after surgery was 84.31% and 58.06%, respectively. Significant postoperative differences as measured by CT scan were observed in four male OSAHS patients, but only one female patient. Conclusions CT measurements of the upper airway of OSAHS patients could help predict the severity of OSAHS. This study revealed a significant difference between the upper airway measurements of men and women. Individualized treatments should consider gender as a factor.

Key words: Obstructive sleep apnea hypopnea syndrome, Hyoid, Polysomnography, X-ray computed tomography, Gender, H-uvulopalatopharyngoplasty

CLC Number: 

  • R766.7
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