Abstract: Objective To investigate the demographic features and clinical manifestations of polypoidal choroidal vasculopathy(PCV). Methods We retrospectively reviewed 107 eyes in 87 consecutive outpatients with a diagnosis of PCV in the Department of Ophthalmology, Shandong Provincial Hospital from August 11, 2011 to January 28, 2015. All the patients underwent an epidemiological inquiry, routine eye examination, color fundus photography fluorescein angiography and indocyanine green angiography(ICGA). Results Among the 87 PCV patients, there was a male predominance with 50(57.5%)male patients. 67(77.0%)patients were affected unilaterally. The average age was 66.4±9.4 years old(range, 41-92). Based on fundus examination, the commonest clinical fundus feature was hemorrhagic pigment epithelial detachment(PED)(55 eyes, 51.4%), which was followed by sub-retinal orange-red bulging lesions(49 eyes, 45.8%). ICGA showed that polyps located in the macular area in 83(77.6%)eyes. The average number of polypoidal lesions was 2.71±1.79(ranged from 1 to 8). The mean area of the solitary polyp and the largest one of multiple polyps was 0.52±0.35 mm², 0.49±0.37 mm² respectively. Conclusion Among our patients with PCV, male, unilateral, macular location of polypoidal lesions with hemorrhagic PED and sub-retinal orange-red bulging lesion are the commonest clinical fundus manifestations. In ICGA, the mean area of PCV with solitary polyp was larger than the biggest one of PCV with multiple polyps.

Key words: Polypoidal choroidal vasculopathy, Fluorescein fundus angiography, Indocyanine green angiography, Clinical manifestation