SMILE术中第二术眼不同保护措施泪膜稳定性的对比研究

doi:10.6040/j.issn.1673-3770.1.2020.004

Abstract

Abstract: Objective To observe the changes in the first non-invasive keratograph tear break-up time(NIKBUTf)and average non-invasive keratograph tear break-up time(NIKBUTav)of the non-operative eye with different protective measures during small incision lenticule extraction(SMILE)using the Keratograph 5M ocular surface analyzer and to observe the effects of different protective measures on tear film stability. Methods A prospective cohort study was conducted. From September 2019 to November 2019, patients who underwent SMILE in the Chongqing Vision Institute were included. The left eye was the observation eye. During SMILE of the right eye, the left eye was protected using deproteinized calf blood eye gel or eyeshade. The control group did not receive protective measures. The NIKBUTf and NIKBUTav of the left eye were measured using the Keratograph 5M ocular surface analyzer before and after the surgery of the right eye. SPSS 25.0 was used for statistical analysis. Results Thirty-five patients accounting for 35 left eyes were included in the study, of which 12 were allocated to the gel group, 11 to the eyeshade group, and 12 to the blank control group. Per the results of repeated-measurement analysis of variance, the variations in the NIKBUTf and NIKBUTav were significant in each group regarding time and grouping(P<0.05). These two parameters also showed an interaction between time and grouping(P<0.05). There was no significant difference in the left eye NIKBUTf of the gel group before and after surgery of the right eye(P>0.05). The NIKBUTav of the left eye in the gel group was longer immediately after surgery of the right eye(P<0.05). In the eyeshade and blank control groups, both the NIKBUTf and NIKBUTav in the left eye decreased immediately after surgery of the right eye(P<0.05). In the control group, the reductions in the NIKBUTf and NIKBUTav were the most significant(P<0.05). Conclusion Different protective measures and time changes had an impact on the NIKBUTf and NIKBUTav. The protective measure of deproteinized calf blood eye gel in the non-operative eyes during SMILE played a protective role in the stability of the tear film. The protective effect of eyeshade on the tear film of the non-operative eye was not obvious, and the stability of the tear film was the worst during the conventional surgery with no protective measures for the non-operative eye.

Key words: Small incision lenticule extraction, Non-operative eye, Tear film stability

CLC Number:

R777

ZHANG Tao, CAO Kaiwei, LIU Lina, LIU Ting, BAI Ji. Comparative study of the effects of different protective measures of the non-operative eye during SMILE surgery on tear film stability[J].Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(2): 32-35.

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Comparative study of the effects of different protective measures of the non-operative eye during SMILE surgery on tear film stability

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