JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY)

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Effect of uvulopalatopharyngoplasty on high sensitive C-creative protein in the serum of patients with obstructive sleep apnea hypopnea

WENG Yong-cai1，LIU Ji-xiang2，WANG Lin2   

  1. 1. Tianjin Medical University, Tianjin 300070, China；2.Department of Otorhinolarygology, Tianjin People′s Hospital, Tianjin 300121
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-10-24 Published:2007-10-24
  • Contact: WENG Yong-cai

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Abstract: Objective To explore the effects of uvulopalatopharyngoplasty(UPPP) on high sensitive C-creative protein(hs-CRP) in serum of patients with obstructive sleep apnea hypopnea syndrome(OSAHS). Method Before and three months after the operations, serum hs-CRP was determined in the experimental group (n=20) and two control groups. Result The serum level of hs-CRP in OSAHS patients was significantly higher than that of the control groups and it was significantly decreased three months after UPPP. Conclusion UPPP can obviously decrease the level of hs-CRP of OSAHS patients; therefore it reduces the incidence of cardiovascular disease of OASHS patients.

Key words: Uvulopalatopharyngoplasty, hs-CRP, Sleep apnea hypopnea syndrome, obstructive

CLC Number: 

  • R766.7
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