JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2010, Vol. 24 ›› Issue (3): 36-39.

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Detection of EOS in nasal section of the early stage in patients with allergic rhinitis treated with sublingual specific immunotherapy

MENG Qinghua, XIE Jinghua, SU Fang, WANG Lei   

  1. Department of Otolaryngology, Guangzhou First People′s Hospital, Guangzhou 510000, Guangdong, China
  • Received:2010-03-10 Revised:2010-05-17 Online:2010-06-16 Published:2010-06-16

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Abstract:

Objective  To explore the relationship in early stage between EOS in the nasal section and clinic syndromes in patients with allergic rhinitis treated with sublingual specific immunotherapy. Methods  43 patients with allergic rhinitis treated with sublingual specific immunotherapy were enrolled in this study. EOS account in the nasal sections was carried out before the treatment and 2,4 and 8 weeks after the treatment. Result  After 4 and 8 weeks, expression of EOS in the nasal section in all cases and in cases with alleviation of clinic syndromes was statistically decreased（P<0.05）. Conclusion  The local immune status of nasal mucosa has been changed after 4 week sublingual immunotherapy in patients with allergic rhinitis.

Key words: Allergic rhinitis; Eosinophils; Immunotherapy; Mite

CLC Number: 

  • R765.21
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