Abstract:

Objectiv  eTo compare the therapeutic effects of simple pterygium excision,  pterygium excision combined with mitomycin C, limbus corneae stem cell transplantation, or amniotic membrane transportation on pterygium.  Methods  168 eyes of 158 patients were divided into four groups, i.e.  groups A，B, C and D, in terms of  applied treatments．41 eyes (group A)，42 eyes (group B), 44 eyes (group C)  and 41 eyes ( group D) were treated with simple pterygium excision, pterygium excision combined with mitomycin C, limbus corneae stem cell transplantation, or  amniotic membrane transportation,  respectively．The patients were followed up from 6 months to one year．Results  The recurrence rates of pterygium in groups A，B, C and D were 17.1%，9.5%, 4.5% and 4.9%，respectively．The difference between group A and the other three groups(B,C and D)was statistically significant (P<0．05)，whereas there was no statistical significance between group B & C ，group  B & D and group C & D. Group C had fewer complications than the other three groups. Conclusion  Pterygium excision combined with limbus corneae stem cell transplantation is the preferable methods while it demonstrates better costeffectiveness, lowere recurrence rate, shorter corneal epithelial healing time and fewer complications.

Key words: Pterygium; Mitomycin C; Conjunctival flap with corneal Limbus transplantation; Amniotic membrane transplantation