JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY)

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Fundus angiography with fluorescein and optical coherence tomography in Stargardt′s disease

PAN Xue-mei, WANG Xing-rong, YUAN Ming-jun   

  1. Eye Center of Shandong University of Traditional Chinese Medicine, Shandong Shierming Eye Hospital, Jinan 250002, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2008-04-24 Published:2008-04-24
  • Contact: PAN Xue-mei

Abstract: To determine the characteristics of the results of fluorescein angiography (FFA) and optical coherence tomography (OCT) in Stargardt′s disease(STGD). Methods7 patients (14 eyes) with Stargardt′s were diagnosed by ocular fundus photochromy, and 6 patients (12 eyes) received FFA and 7 patients (14 eyes) received OCT. ResultsPigment was disordered at the macula in 4 eyes by ophthalmoscopy. A “dark choroid" and window defect (bulls-eye pattern hyperfluorescence) were found by FFA, yellow-white fleck lesions were found in the pole in 8 eyes by ophthalmoscopy, also hypofluorescent became more apparent in the later phase by FFA, and the retina was reduced or deleted in 14 eyes by OCT.  ConclusionFFA combined with OCT is useful for studying the clinical features and pathological mechanism of Stargardt's disease.

Key words: Fluorescein angiography, Optical coherence tomographyStargardt , Stargardt′s disease

CLC Number: 

  • R774.5
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