JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2017, Vol. 31 ›› Issue (4): 90-93.doi: 10.6040/j.issn.1673-3770.0.2016.297

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Clinical observations of Ex-PRESS glaucoma filtration device implantation in patients with glaucoma.

XU Xiao   

  1. Liaocheng Guangming Eye Hospital, Liaocheng 252000, Shandong, China
  • Received:2016-07-03 Online:2017-08-16 Published:2017-08-16

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Abstract: Objective To explore the ocular hypotensive efficacy of Ex-PRESS glaucoma filtration device implantation in patients with glaucoma and its effect on corneal endothelial cell counts. Methods Sixty-two patients with glaucoma treated at our hospital were divided into the control and research groups. The control group comprised 31 patients(33 eyes)treated with compound trabeculectomy, and the research group comprised 31 patients(35 eyes)treated with Ex-PRESS glaucoma filtration device implantation. Results The total surgical success rate was significantly higher in the research group(88.57%)than in the control group(66.67%; P<0.05). Although the vision of patients in both groups improved significantly at 6 months after the operations(P<0.05), improvement was significantly better in the research group(85.71%)than in the control group(60.61%; P<0.05). The intraocular pressure in both groups was significantly lower after operation than before(P<0.05). However, at 1, 3, and 6 months after operation, the intraocular pressure was significantly lower in the research group than in the control group(P<0.05). The corneal endothelial cell counts in both groups were significantly lower at 1, 3, and 6 months after operation than before(P<0.05). No significant intergroup difference in corneal endothelial cell counts was observed at 1, 3, and 6 months after operation(P>0.05). The complication rate was significantly lower in the research group(17.14%)than in the control group(45.45%; P<0.05). Conclusion In patients with glaucoma, the long-term effects of Ex-PRESS glaucoma filtration device implantation on intraocular pressure were superior to those of trabeculectomy, and the effects of both treatments on corneal endothelial cell counts were comparable.

Key words: Ex-PRESS glaucoma filtration deviceimplantation, Trabeculectomy, Glaucoma, Corneal endothelial cell

CLC Number: 

  • R779.6
[1] 刘艳艳,余涵. 原发性急性闭角型青光眼患者持续高眼压状态下行复合式小梁切除术疗效分析[J]. 新乡医学院学报,2015,32(2):160-162. LIU Yanyan, YU Han. Effect of compound trabeculectomy on acute primary angle closure glaucoma under continuous high intraocular pressure state[J]. J Xinxiang Med Univ, 2015, 32(2):160-162.
[2] Kyari F, Abdull MM, Bastawrous A, et al. Epidemiology of glaucoma in sub-saharan africa: prevalence,incidence and risk factors[J]. Middle East Afr J Ophthalmol, 2013, 20(2):111-125.
[3] Quigley HA, Cone FE. Development of diagnostic and treatment strategies for glaucoma through understanding and modification of scleral and lamina cribrosa connective tissue[J]. Cell Tissue Res, 2013, 353(2):231-244.
[4] 汤晓东. 复合式与传统小梁切除术治疗青光眼疗效的比较[J]. 医学综述,2014,20(17):3260-3262. TANG Xiaodong. Comparison on the effects of two kinds of trabeculectomy in the treatment of glaucoma[J]. Med Recap, 2014, 20(17):3260-3262.
[5] 张秀兰. 在中国Ex-PRESS青光眼微型引流器植入术是否可以取代小梁切除术?[J]. 中华实验眼科杂志,2015,33(3):193-195. ZHANG Xiulan. Could Ex-PRESS miniature implantation replace the trabeculectomy in China?[J]. Chin J Exper Ophthalmol, 2015, 33(3):193-195.
[6] 韩光杰,周和政,张文强,等. Ex-PRESS引流钉植入术与小梁切除术治疗开角型青光眼的早期疗效比较[J]. 眼科新进展,2014,34(8):758-760. HAN Guangjie, ZHOU Hezheng, ZHANG Wenqiang, et al. Comparison of therapeutic effect in early stage between Ex-PRESS implantation and trabeculectomy for open angle glaucoma[J]. Recent Adv Ophthalmol, 2014, 34(8):758-760.
[7] 陈红,田爱军. 丝裂霉素C在青光眼治疗中的应用[J]. 海南医学,2014,25(2):236-238.
[8] Wilczynski M, Drobniewski I, Synder A, et al. Evaluation of early corneal endothelial cell loss in bimanual microincision cataract surgery(MICS)in comparison with standard phacoemulsification[J]. Eur J Ophthalmol, 2006, 16(6):798-803.
[9] 林剑鸿. 超声乳化人工晶状体植入术治疗白内障合并青光眼的临床观察[J]. 国际眼科杂志,2014,14(6):1071-1073. LIN Jianhong. Clinical observation of phacoemulsification and IOL implantation for cataract patients with glaucoma[J]. Inter Eye Sci, 2014, 14(6):1071-1073.
[10] 叶汉元,曾云,李鸿翎. EX-PRESS青光眼引流器植入术治疗原发性开角型青光眼[J]. 眼科新进展,2015,35(1):59-62. YE Hanyuan, ZENG Yun, LI Hongling. EX-PRESS glaucoma filtration device implantation for primary open angle glaucoma[J]. Recent Advs Ophthalmol, 2015, 35(1):59-62.
[11] Lisboa R, Mansouri K, Zangwill LM, et al. Likelihood ratios for glaucoma diagnosis using spectral domain optical coherence tomography[J]. Am J Ophthalmol, 2013, 156(5):918-926.
[12] 韩光杰,周和政,张文强,等. P50型与P200型Ex-PRESS引流器植入术对开角型青光眼疗效及安全性的随机对照研究[J]. 中华实验眼科杂志,2015,33(3):246-249. HAN Guangjie, ZHOU Hezheng, ZHANG Wenqiang, et al. Early effectiveness of P50 and P200 Ex-PRESS glaucoma drainage device implantation for open angle glaucoma:a randomized controlled study[J]. Chin J Exper Ophthalmol, 2015, 33(3):246-249.
[13] 陈建丽,韩英军,张满红,等. 同轴微切口超声乳化联合小梁切除术治疗青光眼合并白内障的疗效分析[J]. 眼科新进展,2014,34(1):74-77. CHEN Jianli, HAN Yingjun, ZHANG Manhong, et al. Clinical efficacy of coaxial micro-incision phacoemulsification combined with trabeculectomy for cataract and glaucoma[J]. Recent Adv Ophthalmol, 2014, 34(1):74-77.
[14] Huerva V, Soldevila J, Ascaso FJ, et al. Evaluation of the Ex-PRESS P-50 implant under scleral flap in combined cataract and glaucoma surgery[J]. Int J Ophthalmol, 2016, 9(4):546-550.
[15] Mariotti C, Dahan E, Nicolai M, et al. Response to: RE: Long-term outcomes and risk factors for failure with the EX-press glaucoma drainage device[J]. Eye(Lond), 2014, 28(8):1034-1035.
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