Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2019, Vol. 33 ›› Issue (1): 77-80.doi: 10.6040/j.issn.1673-3770.1.2018.031

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Correlation between PM2.5 and upper airway resistance in patients with allergic rhinitis

JIN Xing1, HU Dayu2, ZHU Li1, DENG Furong2, LIU Junxiu1   

  1. School of Public Health, Peking University Health Science Center, Beijing 100191, China
  • Online:2019-01-20 Published:2019-01-28

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Abstract: Objective To investigate the relationship between upper airway resistance and the concentration of atmospheric particulate matter with diameter <2.5 micrometers(PM2.5)in patients with allergic rhinitis(AR). Methods Sixty patients with clinically diagnosed AR were randomly selected for nasal acoustic reflex and nasal resistance measurement. The PM2.5 concentration in their living areas was continuously monitored. Using SPSS 20.0 statistical software, multiple linear regression models were used. The patient's total nasal resistance, nasal volume, and nasal minimum cross-sectional area were correlated with the air pollution exposure levels. The level of significance was set at P<0.05. Results Nasal acoustic reflex and nasal resistance measurements showed that the total nasal resistance, nasal minimum cross-sectional area, and nasal volume of the subject varied dynamically with varying PM2.5 concentration, and the difference was statistically significant. Conclusion The concentration of PM2.5 affects the upper airway resistance of patients with AR. The greater the concentration of PM2.5 and longer the exposure time, the greater the upper airway resistance of patients with AR.

Key words: Allergic rhinitis, Fine particulate matter, Upper airway resistance, Nasal acoustic reflex, Nasal resistance measurement

CLC Number: 

  • R765.2
[1] Baxter LK, Duvall RM, Sacks J. Examining the effects of air pollution composition on within region differences in PM2.5 mortality risk estimates[J]. J Expo Sci Environ Epidemiol, 2013, 23(5):457-465. doi:10.1038/jes.2012.114.
[2] Bedeschi E, Campari C, Candela S, et al. Urban air pollution and respiratory emergency visits at pediatric unit, Reggio Emilia, Italy[J]. J Toxicol Environ Health Part A, 2007, 70(3/4):261-265. doi:10.1080/15287390600884784.
[3] Krewski D, Burnett R, Jerrett M, et al. Mortality and long-term exposure to ambient air pollution: ongoing analyses based on the American Cancer Society cohort[J]. J Toxicol Environ Health Part A, 2005, 68(13/14):1093-1109. doi:10.1080/15287390590935941.
[4] Cohen AJ, Ross Anderson H, Ostro B, et al. The global burden of disease due to outdoor air pollution[J]. J Toxicol Environ Health Part A, 2005, 68(13/14):1301-1307. doi:10.1080/15287390590936166.
[5] Samet J, Krewski D. Health effects associated with exposure to ambient air pollution[J]. Journal of Toxicology and Environmental Health, Part A, 2007, 70(3/4):227-242. doi:10.1080/15287390600884644.
[6] Castro TM, Marinho DR, Cavalcante CC. The impact of environmental factors on quality of life and symptoms of children with allergic rhinitis[J]. Braz J Otorhinolaryngol, 2013, 79(5):569-574. doi:10.5935/1808-8694.20130102.
[7] Bousquet J, Schünemann HJ, Samolinski B, et al. Allergic Rhinitis and its Impact on Asthma(ARIA): achievements in 10 years and future needs[J]. J Allergy Clin Immunol, 2012, 130(5):1049-1062. doi:10.1016/j.jaci.2012.07.053.
[8] Azalim S, Camargos P, Alves AL, et al. Exposure to environmental factors and relationship to allergic rhinitis and/or asthma[J]. Ann Agric Environ Med, 2014, 21(1):59-63.
[9] Porebski G, Wozniak M, Czarnobilska E. Residential proximity to major roadways is associated with increased prevalence of allergic respiratory symptoms in children[J]. Ann Agric Environ Med, 2014, 21(4):760-766. doi:10.5604/12321966.1129929.
[10] 曹春婷, 张罗. 鼻声反射测量[J]. 中国耳鼻咽喉头颈外科, 2014, 21(8):407-410.
[11] 吴婧. 鼻阻力和鼻声反射鼻腔测量在变应性鼻炎中的临床应用研究[D]. 北京: 北京中医药大学, 2016.
[12] Yao L, Lu N. Spatiotemporal distribution and short-term trends of particulate matter concentration over China, 2006-2010[J]. Environ Sci Pollut Res Int, 2014, 21(16):9665-9675. doi:10.1007/s11356-014-2996-3.
[13] Rutkowski K, Sowa P, Rutkowska-Talipska J, et al. Allergic diseases: the price of civilisational progress[J]. Postepy Dermatol Alergol, 2014,31(2):77-83. doi:10.5114/pdia.2014.40936.
[14] Thompson EA, Sayers BC, Glista-Baker EE, et al. Role of signal transducer and activator of transcription 1 in murine allergen-induced airway remodeling and exacerbation by carbon nanotubes[J]. Am J Respir Cell Mol Biol, 2015, 53(5):625-636. doi:10.1165/rcmb.2014-0221OC.
[15] Takizawa H. Impact of air pollution on allergic diseases[J]. Korean J Intern Med, 2011, 26(3):262-273. doi:10.3904/kjim.2011.26.3.262.
[16] Sierra-Vargas MP, Teran LM. Air pollution: impact and prevention[J]. Respirology, 2012, 17(7):1031-1038. doi:10.1111/j.1440-1843.2012.02213.x.
[17] Nikasinovic L, Just J, Sahraoui F, et al. Nasal inflammation and personal exposure to fine particles PM2.5 in asthmatic children[J]. J Allergy Clin Immunol, 2006, 117(6):1382-1388. doi:10.1016/j.jaci.2006.03.023.
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