Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2022, Vol. 36 ›› Issue (3): 245-255.doi: 10.6040/j.issn.1673-3770.0.2021.422

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Analysis of proportion of outpatients with allergic rhinitis during the coronavirus infectious disease 2019 pandemic

GONG Xiaoyang1,2, CHENG Lei1,2   

  1. 1. Department of Otorhinolaryngology, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, Jiangsu, China;
    2. Department of Clinical Allergy Center, The First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, Jiangsu, China
  • Published:2022-06-15

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Abstract: Objective This study aimed to explore the proportion of outpatients with allergic rhinitis(AR)during the coronavirus infectious disease 2019(COVID-19)pandemic, analyze the relevant factors affecting the incidence of AR during the COVID-19 pandemic, and discuss the impact of staying indoors and wearing masks on the incidence of AR. Methods We collected data from the outpatients in the clinic of the Otolaryngology Department of Jiangsu Province Hospital in March, April, and May of 2017, 2018, 2019, and 2020 and total number of patients who were diagnosed with “AR,” and “chronic rhinitis.” We analyzed the proportion of patients with AR among the total number of patients, and further analyzed the differences in the incidence of AR by sex and age. Results The proportion of outpatients with AR in the total number of outpatients in March, April, and May before the COVID-19 pandemic in 2020 was statistically significant compared to that in April 2018(P=0.028)and May 2019(P=0.001)due to the low number of patients in March, while the differences in other months were not statistically significant. However, the peak of the total number of patients was delayed due to the impact of the COVID-19 pandemic. The proportion of male patients with AR was slightly higher than that of the female patients with AR, with no statistical significance compared to previous years. Regarding age, the proportion of patients with AR in the aged 0-18 years group was higher than that in previous years, and the difference was statistically significant(P<0.05). The aged 19-40years and 41-60 years groups showed no statistical significance compared to previous years, while the sample size of the aged >60 years group was limited and the proportion changed greatly. After the COVID-19 pandemic stabilized in June 2020, the visits of patients with AR gradually approached and partially exceeded the level of the same period from 2017 to 2019. Conclusions During the COVID-19 pandemic in 2020, the proportion of outpatients with AR in the total number of outpatients did not decrease due to factors, such as mask sealing problems, epidemic pressure, indoor allergens, and indoor air conditions, but slightly increased in some months after the COVID-19 pandemic stabilized compared to the past 3 years. Wearing masks and home quarantine did not significantly reduce the onset of the number of patients with AR, but it is still recommended in patients with AR to wear a face mask when going out, especially since pollen allergies during the sensitization pollen spread out, recommends wearing particulate respirators, keep the room ventilated, and purify indoor air, to alleviate AR-related symptoms.

Key words: Rhinitis, Allergic rhinitis, COVID-19, Outpatients, Masks

CLC Number: 

  • R765.22
[1] World Health Organization. Coronavirus disease(COVID-2019)situation reports[EB/OL].(https://www.who.int/emergencies/diseases/novel-coronavirus-2019/situation-reports/)
[2] Wu ZY, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019(COVID-19)outbreak in China: summary of a report of 72 314 cases from the Chinese center for disease control and prevention[J]. JAMA, 2020, 323(13): 1239-1242. doi:10.1001/jama.2020.2648.
[3] Greiner AN, Hellings PW, Rotiroti G, et al. Allergic rhinitis[J]. Lancet, 2011, 378(9809): 2112-2122. doi:10.1016/S0140-6736(11)60130-X.
[4] Canonica GW, Bousquet J, Mullol J, et al. A survey of the burden of allergic rhinitis in Europe[J]. Allergy, 2007, 62(Suppl 85): 17-25. doi:10.1111/j.1398-9995.2007.01549.x.
[5] Bousquet J, Khaltaev N, Cruz AA, et al. Allergic Rhinitis and its Impact on Asthma(ARIA)2008 update(in collaboration with the World Health Organization, GA(2)LEN and AllerGen)[J]. Allergy, 2008, 63(Suppl 86): 8-160. doi:10.1111/j.1398-9995.2007.01620.x.
[6] Wang XD, Zheng M, Lou HF, et al. An increased prevalence of self-reported allergic rhinitis in major Chinese cities from 2005 to 2011[J]. Allergy, 2016, 71(8): 1170-1180. doi:10.1111/all.12874.
[7] Ren JJ, Pang WD, Luo YX, et al. Impact of allergic rhinitis and asthma on COVID-19 infection, hospitalization, and mortality[J]. J Allergy Clin Immunol Pract, 2022, 10(1): 124-133. doi:10.1016/j.jaip.2021.10.049.
[8] Yang JM, Koh HY, Moon SY, et al. Allergic disorders and susceptibility to and severity of COVID-19: a nationwide cohort study[J]. J Allergy Clin Immunol, 2020, 146(4): 790-798. doi:10.1016/j.jaci.2020.08.008.
[9] 宋岚. 花粉调查在花粉症防治中的必要性[J]. 现代预防医学, 2013, 40(2): 370-371, 375.
[10] 欧阳昱晖, 范尔钟, 李颖, 等. 春季花粉浓度对过敏性鼻炎患者的影响[J]. 中国耳鼻咽喉头颈外科, 2011, 18(12): 628-630. doi:10.16066/j.1672-7002.2011.12.011. OUYANG Yuhui, FAN Erzhong, LI Ying, et al. Effects of spring pollen concentration on allergic rhinitis subjects in Beijing[J]. Chinese Archives of Otolaryngology-Head and Neck Surgery, 2011, 18(12): 628-630. doi:10.16066/j.1672-7002.2011.12.011.
[11] 万远芳, 刁庆春. 法国梧桐花粉及其变应原研究进展[J]. 中国中西医结合皮肤性病学杂志, 2008, 7(2): 128-130. doi:10.3969/j.issn.1672-0709.2008.02.034.
[12] Yamamoto H, Yamada T, Sakashita M, et al. Efficacy of prophylactic treatment with montelukast and montelukast plus add-on loratadine for seasonal allergic rhinitis[J]. Allergy Asthma Proc, 2012, 33(2): e17-e22. doi:10.2500/aap.2012.33.3514.
[13] Tovey ER, Chapman MD, Platts-Mills TA. Mite faeces are a major source of house dust allergens[J]. Nature, 1981, 289(5798): 592-593. doi:10.1038/289592a0.
[14] 常生, 赵娟芝. 我国医用口罩标准对比解读[J]. 针织工业, 2020(3): 14-17. CHANG Sheng, ZHAO Juanzhi. Comparison and index analysis of medical mask standards in China[J]. Knitting Industries, 2020(3): 14-17.
[15] Lee SA, Hwang DC, Li HY, et al. Particle size-selective assessment of protection of European standard FFP respirators and surgical masks against particles-tested with human subjects[J]. J Healthc Eng, 2016:8572493. doi:10.1155/2016/8572493.
[16] He XJ, Reponen T, McKay R, et al. How does breathing frequency affect the performance of an N95 filtering facepiece respirator and a surgical mask against surrogates of viral particles? [J]. J Occup Environ Hyg, 2014, 11(3): 178-185. doi:10.1080/15459624.2013.848037.
[17] Dror AA, Eisenbach N, Marshak T, et al. Reduction of allergic rhinitis symptoms with face mask usage during the COVID-19 pandemic[J]. J Allergy Clin Immunol Pract, 2020, 8(10): 3590-3593. doi:10.1016/j.jaip.2020.08.035.
[18] Heinrich J. Influence of indoor factors in dwellings on the development of childhood asthma[J]. Int J Hyg Environ Health, 2011, 214(1): 1-25. doi:10.1016/j.ijheh.2010.08.009.
[19] Liu C, Zhang Y, Benning JL, et al. The effect of ventilation on indoor exposure to semivolatile organic compounds[J]. Indoor Air, 2015, 25(3): 285-296. doi:10.1111/ina.12139.
[20] Piekarska B, Furmańczyk K, Jaworski S, et al. Building age, type of indoor heating and the occurrence of allergic rhinitis and asthma[J]. Postepy Dermatol Alergol, 2020, 37(1): 81-85. doi:10.5114/ada.2019.85288.
[21] Duan J, Wang X, Zhao DS, et al. Risk effects of high and low relative humidity on allergic rhinitis: time series study[J]. Environ Res, 2019, 173: 373-378. doi:10.1016/j.envres.2019.03.040.
[22] Li YS, Hu HS, Zhang T, et al. Increase in indoor inhalant allergen sensitivity during the COVID-19 pandemic in South China: a cross-sectional study from 2017 to 2020[J]. J Asthma Allergy, 2021, 14: 1185-1195. doi:10.2147/JAA.S322034.
[23] 袁峰. 影响变应性鼻炎发病及预后的相关危险因素Logistic回归分析[J]. 中国耳鼻咽喉颅底外科杂志, 2017, 23(3): 266-270. doi:10.11798/j.issn.1007-1520.201703017. YUAN Feng. Logistic regression analysis of risk factors affecting the incidence and prognosis of allergic rhinitis[J]. Chinese Journal of Otorhinolaryngology-Skull Base Surgery, 2017, 23(3): 266-270. doi:10.11798/j.issn.1007-1520.201703017.
[24] Kwon JA, Lee M, Yoo KB, et al. Does the duration and time of sleep increase the risk of allergic rhinitis? Results of the 6-year nationwide Korea youth risk behavior web-based survey[J]. PLoS One, 2013, 8(8): e72507. doi:10.1371/journal.pone.0072507.
[25] Rhee CS, Wee JH, Ahn JC, et al. Prevalence, risk factors and comorbidities of allergic rhinitis in South Korea: the Fifth Korea National Health and Nutrition Examination Survey[J]. Am J Rhinol Allergy, 2014, 28(2): e107-e114. doi:10.2500/ajra.2014.28.4040.
[26] Osman M. Therapeutic implications of sex differences in asthma and atopy[J]. Arch Dis Child, 2003, 88(7): 587-590. doi:10.1136/adc.88.7.587.
[27] 梁慧敏, 汪李琴, 万文锦, 等. 耳鼻咽喉科内镜室新型冠状病毒感染防控方案的探讨与实践[J]. 山东大学耳鼻喉眼学报, 2020, 34(2): 88-92. doi:10.6040/j.issn.1673-3770.0.2020.078. LIANG Huimin, WANG Liqin, WAN Wenjin, et al. COVID-19 prevention and control scheme in an ENT endoscopy unit in China[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(2): 88-92. doi:10.6040/j.issn.1673-3770.0.2020.078.
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