Abstract: To investigate internet-related factors on quality of tear film in adolescence. MethodsEpidemiological questionnaires were used by 533 young people in 7 net bars in Jinan City. The Schirmer1 test and break -up time (BUT) were determined. Multiple linear regression and stepwise regression were used to analyze the data. Results1. 40% of the males had abnormal Schirmer test results and 21.33% of them occurred in both eyes. 96% of the males had abnormal BUT and 84% of them occurred in both eyes. 57.12% of the females had abnormal Schirmer test results and 85.71% had abnormal BUT, and all occurred on binoculus. 2. 52.81% of them had visual fatigue. 3. The greatest risk factor is time of using the internet. The Schirmer test result was 0.19 and the BUT 0.20. Conclusions1. A long internet terminal use history and long time on net are key reasons for the decrease of tear secretion. 2. Abnormal BUT is common in adolescence during internet terminal use. 3. Internet games and monitors are important factors influencing quality of the tear film. 4. Most female net users have poor quality of tear film on binoculus.

Key words: Break-up time, Tear film, Schirmer1 test, Adolescence, Online