JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2015, Vol. 29 ›› Issue (1): 49-51.doi: 10.6040/j.issn.1673-3770.0.2014.342

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Effects of 01% cyclosporin eye drops in combination with sodium hyaluronate eye drops in the treatment of dry eye syndrome

ZHANG Ju, WU Xin-yi   

  1. Department of Ophthalmology, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China
  • Received:2014-10-19 Online:2015-02-16 Published:2015-02-16

Abstract: Objective To evaluate the effects of 0.1% cyclosporin eye drops in combination with sodium hyaluronate eye drops in the treatment of dry eye syndrome. Methods A total of 60 patients (120 eyes) with dry eye syndrome were randomly divided into the experimental group (60 eyes) treated by 0.1%cyclosporin eye drops in combination with sodium hyaluronate eye drops and the control group (60 eyes) treated by bysodium hyaluronate eye drops. Both groups were measured the Schirmer I test(SIt), tear film break-up time(BUT) and corneal fluorescein staining(FLs) before and after a month. Results There were no significant differences between the experimental group and the control group in SIt, BUT and FLs before treatment (P>0.05). After treatment, all the indicators of SIt, BUT and FLs of the experimental group and the control group were better than before (P<0.05). The experimental group was superior to the control group in the three indicators (SIt, BUT and FLs)(P<0.05). Conclusion 0.1%cyclosporin eye drops in combination with sodium hyaluronate eye drops is effective in treatment of dry eye, and is superior to bysodium hyaluronate eye drops alone.

Key words: Dry eye syndrome, Cyclosporin eye drops, Artificial tears

CLC Number: 

  • R777.2
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