JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2016, Vol. 30 ›› Issue (3): 37-39.doi: 10.6040/j.issn.1673-3770.0.2015.449

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Influence of tracheal infection after total laryngectomy on pulmonary function and tumor recurrence rate in patients with laryngocarcinoma.

JIN Shu   

  1. Department of Otolaryngology, The First Peoples Hospital of Ziyang, Ziyang 614300, Sichuan, China
  • Received:2015-10-28 Online:2016-06-16 Published:2016-06-16

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Abstract: Objective To explore the influence of tracheal infection after total laryngectomy on pulmonary function and tumor recurrence rate in patients with laryngocarcinoma. Methods A total of 276 patients with laryngocarcinoma were selected, in which 149 received total laryngectomy, and 127 received total laryngectomy plus neck lymph node dissection. Postoperative infection, pulmonary function and recurrence conditions of all patients were observed. Results Totally 26(9.42%)patients had postoperative infection, in which the infection rate of patients with total laryngectomy was 4.03%(6/149)whereas that of patients with total laryngectomy plus neck lymph node dissection was 15.75%(20/127), and there was significant difference(P<0.05). The infection rate was 2.11%(3/142)in patients with surgical duration <4 h, 11.76%(11/102)in patients with surgical duration < 4-6 h and 37.50%(12/32)in patients with surgical duration>6 h, and the rate of patients with surgical duration < 4-6 h was markedly lower than that >6 h(P<0.01). Compared with surgery before, forced expiratory volume in 1 second(FEV1)increased obviously while V25 reduced markedly in patients in postoperative tracheal infection group. The tumor recurrence rate was 34.62% in patients with tracheal infection, significantly higher than the 2.00% in those with non-infection(P<0.01). Conclusion Patients with laryngocarcinoma have certain improvement in pulmonary function and risk of infection and recurrence after total laryngectomy, so effective measurements should be conducted to reduce the infection rate and promote patients’ prognosis.

Key words: Laryngocarcinoma, Safety, Tracheal infection, Pulmonary function, Recurrence

CLC Number: 

  • R765.2
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