Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2018, Vol. 32 ›› Issue (6): 56-59.doi: 10.6040/j.issn.1673-3770.0.2018.307

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Clinical effect of Yunpi Huatan Tongqiao decoction on pediatric snoring disease and immune function

YU Yuejin1, GU Jingwen2, HUANG Wei1, LI Pei1, HU Hua1, HAO Yanan1, FAN Yongjiang1, GAO Yiyi1   

  1. Department of Pediatrics, Seventh Peoples Hospital of Shanghai University of TCM, Shanghai 200137, China
  • Published:2018-11-29

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Abstract: Objective To study the clinical effect of activating spleen treatment of nasal prescription on pediatric snoring disease and immune function. Methods Sixty consecutive subjects with pediatric snoring disease were enrolled from May 2016 to December 2017 and divided randomly into control and observation groups, each group comprising of 30 cases. Patients in the control group underwent resective surgery and those in the observation group were administered activating spleen treatment of nasal prescription. The total duration of treatment was 3 months, following which the difference in size of the tonsils were assessed. TCM syndrome scores, the clinical efficacy rate before and after treatment in the two groups, and immunologic parameters including IgA, IgG, and IgM levels in peripheral venous blood were evaluated by ELISA. Results The size of the tonsils was smaller in both groups after treatment with significant reduction in size being observed in the control group(P<0.05). The size of the tonsils was within the normal range in the observation group. Lower post-treatment TCM syndrome scores were observed in the two groups with no statistically significant difference(P>0.05). The efficacy rate was not significantly different between the two groups(P>0.05). Post-treatment, the levels of IgA, IgG, and IgM remained unchanged in the two groups(P>0.05). Conclusion Both treatments, nasal prescription for activation of spleen and resective surgery, can provide comparable clinical effect in cases of pediatric adenoidal hypertrophy with no effect on immune function.

Key words: Yunpi Huatan Tongqiao decoction, Surgery, Snoring disease, TCM syndrome, Immunologic function

CLC Number: 

  • R272
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