Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2019, Vol. 33 ›› Issue (5): 121-124.doi: 10.6040/j.issn.1673-3770.0.2018.529

• Original Article • Previous Articles    

Changes in the ocular biometric parameters before and after cycloplegia in juveniles with different degrees of myopia

Danfeng ZHANG()   

  1. Department of Optometry and Pediatric Ophthalmology, Shanghai Aier Eye Hospital, Shanghai 200336, China
  • Received:2018-11-16 Revised:2019-01-10 Online:2019-09-20 Published:2019-10-15
  • Contact: Danfeng ZHANG E-mail:goodluckdf@163.com

Abstract: Objective

To analyze the changes in refraction and the ocular biometric parameters with cycloplegia in juveniles with different degrees of myopia.

Methods

Fifty-six juveniles with myopia, aged from 7 to 17 years, were enrolled from our optometry outpatient center. Before inducing cycloplegia, refraction, accommodation response, and ocular biometric parameters were measured in all subjects by optical biometry (Lenstar900). Refraction and the ocular biometric parameters were measured again after cycloplegia. The subjects were divided into two groups according to the degree of myopia: low myopia group and moderate-to-high myopia group. We analyzed the differences in the ocular biometric parameters between the two groups and the relationship of these parameters with the age. We also compared the differences in refraction and the ocular biometric parameters between before and after cycloplegia, and analyzed the relationship between those differences and the age and accommodation response.

Results

Before cycloplegia, there was a statistically significant difference in the axial length (AL) between the two groups, and AL showed a significant positive correlation with the age. There was no statistical difference in the aqueous depth (AD), lens thickness (LT), and pupil diameter (PD) between the two groups, and none of these parameters correlated with the age. The differences in the changes in refraction, LT, AL, and PD before and after cycloplegia between the two groups were not statistically significant; however, the difference in the changes in AD was statistically significant.

Conclusion

The differences in the changes in refraction before and after cycloplegia between the two groups were not statistically significant; however, the changes in the AD were significant. Therefore, it is not necessary to measure refraction with cycloplegia in juveniles with myopia; accommodation should be measured instead.

Key words: Myopia, Cycloplegia, Lenstar, Aqueous depth, Lens thickness

CLC Number: 

  • R778.1+1

Table 1

Comparison of the biometric parameters of the two groups (x ± s, mm)"

分组 前房深度(AD) 晶状体厚度(LT) 眼轴(AL) 瞳孔直径(PD)
轻度近视组(n=37) 3.22 ± 0.19 3.37 ± 0.18 24.06 ± 0.82 5.92 ± 0.92
中重度近视组(n=19) 3.26 ± 0.19 3.37 ± 0.17 25.78 ± 0.82 5.54 ± 0.85
t -0.71 0.10 -7.44 1.50
P 0.50 0.92 <0.001 0.14

Table 2

Analysis of correlation between the biometric parameters and the age"

r P
前房深度(AD) -0.221 0.119
晶状体厚度(LT) 0.011 0.939
眼轴(AL) 0.352 0.008
瞳孔直径(PD) -0.120 0.380

Table 3

Comparison of the changes in refraction and biometric parameters (mm)"

分组 屈光度 前房深度(AD) 晶状体厚度(LT) 眼轴(AL) 瞳孔直径(PD)
轻度近视组(n=37)

-0.25

(-0.38~0.00)

-0.04

(-0.06~-0.02)

0.02

(0.01~0.05)

-0.01

(-0.02~0.01)

-1.92

(-2.73~-1.34)

中重度近视组(n=19)

-0.25

(-0.25~0.00)

-0.02

(-0.04~-0.01

0.01

(0.01~0.03)

0.00

(-0.01~0.01)

-2.06

(-2.50~-1.89)

Z -0.75 -2.39 -0.96 -1.19 -1.04
P 0.45 0.02 0.34 0.24 0.30

Table 4

Analysis of correlation between the refraction changes and the AD, LT, AL, PD changes, age, and BCC"

前房深度

AD差值

晶状体厚度

LT差值

眼轴

AL差值

瞳孔直径

PD差值

调节反应 年龄
r 0.281 -0.178 -0.163 0.092 0.102 0.083
P 0.046 0.211 0.268 0.504 0.456 0.542
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