ISSN 1673-3770 CN 37-1437/R
Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2020, Vol. 34 ›› Issue (2): 99-105.doi: 10.6040/j.issn.1673-3770.0.2019.553
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YANG Lijun, LI Lijuan, LIU Tao, WANG Liwei
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| [1] Takao Imai, Noriaki Takeda, Tetsuo Ikezono, et al. Classification, Diagnostic Criteria and Management of Benign Paroxysmal Positional Vertigo[J]. Auris Nasus Larynx, 2017,44(1):1-6. doi:10.1016/j.anl.2016.03.013. [2] 陈太生, 王巍, 徐开旭, 等. 良性阵发性位置性眩晕及其诊断治疗的思考[J]. 山东大学耳鼻喉眼学报,2019,33(5):1-5. doi:10.6040/j.issn.1673-3770.1.2019.053. [3] 施天明, 耿昱. 水平半规管良性阵发性位置性眩晕诊治进展[J]. 中华耳鼻咽喉头颈外科杂志, 2014,49(8):693-697. doi:10.3760/cma.j.jssn.1673-0860.2014.08.016. [4] Wersall J. Studies on the structure and innervation of the sensory epithelium of the cristae ampulares in the Guinea pig; a light and Electron microscopic investigation[J]. Acta Otolaryngol Suppl, 1956, 126: 1-85. [5] Friedmann I. Electron microscope observations on in vitro cultures of the isolated fowl embryo otocyst[J]. J Biophys Biochem Cytol, 1959, 5(2): 263-268. doi:10.1083/jcb.5.2.263. [6] Igarashi M. Architecture of the otolith end organ: some functional considerations[J]. Ann Otol Rhinol Laryngol, 1966, 75(4): 945-955. doi:10.1177/000348946607500403. [7] Carlstrom D, Engstrom H. The ultrastructure of statoconia[J]. Acta Otolaryngol, 1955, 45(1): 14-18. doi:10.3109/00016485509118139. [8] 黄选兆,汪吉宝,孔维佳.实用耳鼻咽喉头颈外科学 [M]. 2版. 北京:人民卫生出版社,2008:687-690. [9] Walther LE, Wenzel A, Buder J, et al. Detection of human utricular otoconia degeneration in vital specimen and implications for benign paroxysmal positional Vertigo[J]. Eur Arch Otorhinolaryngol, 2014, 271(12): 3133-3138. doi:10.1007/s00405-013-2784-6. [10] Andrade LR, Lins U, Farina M, et al. Immunogold TEM of otoconin 90 and otolin-relevance to mineralization of otoconia, and pathogenesis of benign positional Vertigo[J]. Hear Res, 2012, 292(1/2): 14-25. doi:10.1016/j.heares.2012.07.003. [11] Zhao X, Yang H, Yamoah EN, et al. Gene targeting reveals the role of Oc90 as the essential organizer of the otoconial organic matrix[J]. Dev Biol, 2007, 304(2): 508-524. doi:10.1016/j.ydbio.2007.01.013. [12] Lundberg YW, Xu YF, Thiessen KD, et al. Mechanisms of otoconia and otolith development[J]. Dev Dyn, 2015, 244(3): 239-253. doi:10.1002/dvdy.24195. [13] Boyle R, Ehsanian R, Mofrad A, et al. Morphology of the utricular otolith organ in the toadfish, Opsanus tau[J]. J Comp Neurol, 2018, 526(9): 1571-1588. doi:10.1002/cne.24429. [14] Eatock RA, Corey DP, Hudspeth AJ. Adaptation of mechanoelectrical transduction in hair cells of the bullfrog's sacculus[J]. J Neurosci, 1987, 7(9): 2821-2836. [15] Lins U, Farina M, Kurc M, et al. The otoconia of the Guinea pig utricle: internal structure, surface exposure, and interactions with the filament matrix[J]. J Struct Biol, 2000, 131(1): 67-78. doi:10.1006/jsbi.2000.4260. [16] Johnsson LG, Hawkins JE Jr. Sensory and neural degeneration with aging, as seen in microdissections of the human inner ear[J]. Ann Otol Rhinol Laryngol, 1972, 81(2): 179-193. doi:10.1177/000348947208100203. [17] Ross MD, Peacor D, Johnsson LG, et al. Observations on normal and degenerating human otoconia[J]. Ann Otol Rhinol Laryngol, 1976, 85(3 pt 1): 310-326. doi:10.1177/000348947608500302. [18] Walther LE, Westhofen M. Presbyvertigo-aging of otoconia and vestibular sensory cells[J]. J Vestib Res, 2007, 17(2/3): 89-92. [19] Campos A, Cañizares FJ, Sánchez-Quevedo MC, et al. Otoconial degeneration in the aged utricle and saccule[J]. Adv Otorhinolaryngol, 1990, 45: 143-153. doi:10.1159/000418950. [20] Jang YS, Hwang CH, Shin JY, et al. Age-related changes on the morphology of the otoconia[J]. Laryngoscope, 2006, 116(6): 996-1001. doi:10.1097/01.mlg.0000217238.84401.03. [21] Walther LE, Wenzel A, Buder J, et al. Detection of human utricular otoconia degeneration in vital specimen and implications for benign paroxysmal positional Vertigo[J]. Eur Arch Otorhinolaryngol, 2014, 271(12): 3133-3138. doi:10.1007/s00405-013-2784-6. [22] Flock A. Structure of the macula utriculi with special reference to directional interplay of sensory responses as revealed by morphological polarization[J]. J Cell Biol, 1964, 22: 413-431. doi:10.1083/jcb.22.2.413. [23] Highstein SM, Holstein GR. The anatomical and physiological framework for vestibular prostheses[J]. Anat Rec(Hoboken), 2012, 295(11): 2000-2009. doi:10.1002/ar.22582. [24] Curthoys IS, Oman CM. Dimensions of the horizontal semicircular duct, Ampulla and utricle in the human[J]. Acta Otolaryngol, 1987, 103(5/6): 254-261. doi:10.3109/00016488709107791. |
| [1] | To establish a new grade of vestibular function abnormality in patients with Menieres disease(MD)and to preliminarily investigate its clinical significance and correlation with the hearing stage. MethodsClinical data of patients with unilateral intractable MD hospitalized from January to December were retrospectively reviewed. All patients underwent pure-tone audiometry, cervical vestibular-evoked myogenic potential(cVEMP)testing, ocular VEMP(oVEMP)testing, the video head impulse test(vHIT), and the caloric test. Abnormal semicircular canal function was defined as an abnormal vHIT or caloric test result. Abnormal saccule function was defined as an abnormal cVEMP. Abnormal utricle function was defined as an abnormal oVEMP. Vestibular function grade Ⅰ was defined when the utricle, saccule, and semicircular canal were normal. Vestibular function grade Ⅱ was defined when the utricle, saccule, or semicircular canal was abnormal. Vestibular function grade Ⅲ was defined when two structures among the utricle, saccule, and semicircular canal were abnormal. Finally, vestibular function grade Ⅳ was defined when the utricle, saccule, and semicircular canal were all abnormal. ResultsWe enrolled cases of MD, including , , , and cases in stages Ⅰ, Ⅱ, Ⅲ, and Ⅳ, respectively. The pure-tone average(PTA)hearing at Hz, kHz, and kHz was .±. dB HL in the ears with MD. The abnormal rates of cVEMP, oVEMP, vHIT, and caloric test results were .%, .%, .%, and .%, respectively. According to the grade of vestibular function abnormality, , , , and cases were in grades Ⅰ, Ⅱ, Ⅲ, and Ⅳ, respectively. The vestibular function stage significantly correlated with the PTA(Pr=.), MD stage(P., r=.), and disease duration(P=., r=.). The vestibular function stage did not significantly correlate with patient age(P=.). ConclusionThe rates of abnormal otolith and semicircular canal functions increase with the development of MD. Therefore, patients with MD can be accurately assessed with precise testing of the utricle, saccule, and semicircular canals. The status of the development of MD is reflected in the hearing and vestibular function stages. The combined assessment of hearing and vestibular functions can provide a useful reference for the treatment and prognosis of patients with MD.. A new grade of vestibular function abnormality in Menieres disease: a pilot study [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 14-19. |
| [2] | ZHANG Yuzhong, WEI Xinyu, LI Yingqi, CHEN Zichen, XU Yong, CHENG Ying, GAO Ying, CHEN Feiyun, HU Juan, XU Min, ZHANG Qing. Invention and application of subjective visual vertical and horizontal examination software [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2018, 32(6): 60-63. |
| [3] | ZHU Zijian, LIU Qiang. Clinical analysis of 35 cases of lateral semicircular canal benign paroxysmal positional vertigo with transformable-direction eye shock [J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(5): 53-57. |
| [4] | CAI Zhi， ZHENG Shi-xin， GAO Chong-yang. Follicular Dendritic Cell Sarcoma of Tonsil: a case report and review [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2012, 26(1): 55-57. |
| [5] | JI Xiao-bin,LIU Xi-hong,ZANG Lin-quan,WANG Lei,XIE Jun . Ultrastructure of the surfactant lamellar bodies in the nasal mucosa of guinea pigs [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2007, 21(6): 545-547 . |
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