Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2023, Vol. 37 ›› Issue (1): 152-156.doi: 10.6040/j.issn.1673-3770.0.2021.570

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Study on the clinical significance of posterior uveal melanoma biopsy

SUN Hao1,2, YANG Hui3, LI Jiao4   

  1. 1. Medical School of Ophthalmology and Optometry of Shandong University of Traditional Chinese Medicine, Jinan 250002, Shandong, China;
    2. Department of Ophthalmology, Lanling People's Hospital of Linyi City, Linyi 276000, Shandong, China;
    3. Department of Pathology, The Second Affiliated Hospital of Shandong First Medical University, Taian 271000, Shandong, China;
    4. Eye Hospital Affiliated to Shandong University of Traditional Chinese Medicine/ Shandong Institute of Eye Disease Control, Jinan 250002, Shandong, China
  • Published:2023-02-06

Abstract: Posterior uveal melanoma(PUMs), the most common primary intraocular malignant tumor in adults, typically has an early onset that is insidious and asymptomatic. The diagnosis of patients with PUMs at home and abroad is primarily based on clinical features, which are easily missed or misdiagnosed. In recent years, oncologists have commonly used two types of biopsies to confirm the diagnosis of patients with PUMs: fine-needle aspiration biopsy(FNAB)and transvitreal retinochoroidal biopsy(TVRC). At present, there are few systematic studies on the application of FNAB and TVRC in the diagnosis of PUM. This paper reviews the clinical safety, sampling methods, and clinical significance of these two biopsy methods in the diagnosis of PUM.

Key words: Posterior uveal melanomas, Fine-needle aspiration biopsy, Transvitreal retinochoroidal biopsy, Security, Clinical significance

CLC Number: 

  • R779.62
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