Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2025, Vol. 39 ›› Issue (3): 97-103.doi: 10.6040/j.issn.1673-3770.0.2024.519

• Shanghai Sixth Peoples Hospital Otorhinolaryngology & Head and Neck Surgery Department dedicated to “120th Anniversary of the Sixth Hospital” Commemorative Theme • Previous Articles    

Etiology and treatment advances in glottic insufficiency

ZHOU Zhihang1, LIU Suru2, ZHOU Jing1, CHEN Dan1, YANG Jiajing1, LIU Rui1, ZHOU Li3   

  1. 1. School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan, China2. Department of Otorhinolaryngology & Head and Neck Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine / Shanghai Key Laboratory of Sleep Disordered Breathing / Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai 200233, China3. Department of Otorhinolaryngology, Hospital of Chengdu University of TCM / TCM Hospital of Sichuan Province, Chengdu 610072, Sichuan, China
  • Published:2025-06-04

Abstract: Glottic insufficiency refers to the incomplete closure of the bilateral vocal cords in the absence of space-occupying lesions, resulting in air "leakage." The primary manifestations include persistent hoarseness, weak phonation, and a breathy voice. Some patients may also exhibit symptoms such as choking, dysphagia, and even aspiration. The etiologies of glottic insufficiency encompass structural voice disorders, such as vocal fold sulcus and vocal fold scarring, as well as regulatory voice disorders, such as vocal fold paralysis and phonatory fatigue. Clinically, assessment tools often include the voice-related quality of life scale, laryngoscopy, acoustic analysis of the voice, electroglottography, and aerodynamic measurements. For patients suspected of having vocal fold paralysis, laryngeal electromyography is employed. The treatment of glottic insufficiency aims to reduce the glottic gap during phonation, thereby improving the patient's voice quality. This paper reviews the common causes and treatment methods for glottic insufficiency, summarizes the latest advancements in diagnosis and treatment, and provides a reference for clinicians.

Key words: Glottic insufficiency, Etiology, Diagnosis, Vocal cord paralysis

CLC Number: 

  • R767.92
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