Abstract:

Objective To observe the therapeutic effect of drugs on chronic rhinosinusitis with smell disturbance.  Methods  Twenty-six consecutive patients withchronic rhinosinusitis and smell disturbance,encountered between January 2006 and August 2008, were in cluded in this retrospective study. 20 were given Decongestant, Antiinflammatory, and anti-infection therapy and therapy promotingmucus to enduction. On the basic of the above therapy, 5 were given systemic steroids and neural nutrition，and 1 was given systemic steroids， neural nutrition and anti-virus therapy. Olfactory  test, CT in nasal sinus and nasal endoscope examination were given before and after the therapy. Results Among the 26cases, 24(92.00％), were cured; the average time of therapy was 25.64 days.  Conclusion  According to the  etiological factors,  suitable therapy can getsatisfactory therapeutic efficacy for smell disturbance which is the major symptomof chronic rhinosinusitis.

Key words: Therapy；Smell disturbance; Rhinosinusitis; Observation