JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2009, Vol. 23 ›› Issue (4): 49-51.

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Sublingual immunotherapy on allergic rhinitis

 KUANG Jia-Li, TUN Jun, GUO Liang, FANG Xiang-Jia   

  1. Department of Otolaryngology, Zhuhai Second People′s Hospital, Zhuhai 519020, Guangdong, China
  • Received:2009-06-09 Revised:2009-08-03 Online:2009-08-16 Published:2009-08-16

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Abstract:

Objective  To observe the effect of sublingual immunotherapy on allergic rhinitis.  Methods  A randomized, double-clind, parallel-controlled trial was conducted. 70 patients with allergic rhinitis whose test result was positive for dermatophagoides farinae were equally divided into two groups: the experimental group accepted sublingual immunotherapy, and the control group accepted desensitization therapy by regular subcutaneous injection. All patients were followed up fortwo years and the effect was evaluated.  Results  The response rate was 80.0% in the experimental group, and 77.1% in the control group. There was no statistical difference between the two groups(P>0.05). But the symptom score was statistically different after treatment in each group(P<0.01). Conclusion  Sublingual immunotherapy has almost the same good effectiveness as subcutaneous immunotherapy. Forits safety and convenience, it is worth populariz ing in practice.

Key words: Allergic rhinitis; Sublingual immunotherapy; Subcutaneous immunotherapy;   Dermatophagoides farinae

CLC Number: 

  • R765.21
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