Abstract:

Objective   To treat meniere′s disease by intratympanic gentamicin through an inserted catheter and to explore its effect. Methods   A catheter was put into the tympanum through an eustachina tube under nasal endoscopic visualization and it was kept for almost one week. Gentamicin was injected after insertion of catheters into the tympanum and oral steroid hormone was used to protect audition. Patients were observed on the first day, the third day, the seventh day and in three months. Results   After injection of gentamicin, vertigo was relieved the next day, and completely relieved within a week while the recurrence rate was extremely low. Conclusion   Most of retrospective experiments have focused on research about the damage effect of gentamicin to the inner ear cells without paying attention to its therapeutic effect. It was found that it is effective to cure meniere′s disease by intratympanic aminoglycosides antibiotics.

Key words: Meniere′s disease; Gentamicin; Nasal endoscopy