Abstract:

Objective    To explore the method and  curative effectiveness of hormone injection into tympanic cavity in the treatment of sudden hearing loss. Method    Seventy subjects(seventy ears) were divided into two groups randomly, including the trial group (40 subjects; 40 ears) and the control group (30 subjects; 30ears). For the trial group, methylprednisolone and lidocaine were injected into the tympanic cavity three times a week in a course of at least two weeks. The audiometric testing was performed before and after the treatment.  The curative effectiveness was evaluated. Results    In the tial groups, tinnitus was improved in 22 ears. With pure tone audiometry, complete or significant improvement was found in 8 ears, moderate improvement in 19 ears and no improvement in 13 ears. Total efficiency was 67.5%。The control group showed no significant improvement(P<0.01). No unexpected adversary event, such as otitis media, perforated tympanic membrane or worsening in hearing, occurred. Conclusion    The injection of Methylprednisolone and lidocaine into tympanic cavity is effective in the treatment of sudden hearing loss.

Key words: Sudden hearing loss; Hormone injection; Methylprednisolone; Audiometric evaluation; Curative effectiveness