JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2015, Vol. 29 ›› Issue (5): 79-82.doi: 10.6040/j.issn.1673-3770.0.2015.170

Previous Articles     Next Articles

Research progress of miRNA in head and neck cancers

ZHOU Juan, ZHENG Jiafa   

  1. Department of Otorhinolaryngology Head and Neck Surgery, Nanhua Hospital Affiliated to University of South China, Hengyang 421001, Hunan, China
  • Received:2015-04-24 Revised:2015-09-22 Online:2015-10-16 Published:2015-10-16

PDF (PC)

554

Abstract: A microRNA, abbreviated miRNA, is a non-coding single-stranded small molecular RNA. Through incomplete or complete complementary pairing with target mRNA 3' UTR (3' end untranslated region), it plays an important role in the occurrence and development of tumors. This paper reviews the role of miRNA in the diagnosis, prognosis and treatment of head and neck cancers.

Key words: Head and neck cancers, miRNA, Gene

CLC Number: 

  • R739.91
[1] Warnakulasuriya S. Global epidemiology of oral and oropharyngeal cancer[J]. Oral Oncol, 2009, 45(4-5): 309-316.
[2] Nagadia R, Pandit P, Coman W B, et al. miRNAs in head and neck cancer revisited[J]. Cell Oncol (Dordr), 2013, 36(1): 1-7.
[3] Warnakulasuriya S. Causes of oral cancer—an appraisal of controversies[J]. Br Dent J, 2009, 207(10): 471-475.
[4] Lee R C, Feinbaum R L, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14[J]. Cell, 1993, 75(5): 843-854.
[5] Malumbres M. miRNAs and cancer: an epigenetics view[J]. Mol Aspects Med, 2012, 34: 863-874.
[6] Li J, Huang H, Sun L, et al. MiR-21 indicates poor prognosis in tongue squamous cell carcinomas as an apoptosis inhibitor[J]. Clin Cancer Res, 2009, 15(12): 3998-4008.
[7] Yu Z W, Zhong L P, Ji T, et al. MicroRNAs contribute to the chemoresistance of cisplatin in tongue squamous cell carcinoma lines[J]. Oral Oncol, 2010, 46(4): 317-322.
[8] Kozaki K, Imoto I, Mogi S, et al. Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer[J]. Cancer Res, 2008, 68(7): 2094-2105.
[9] Avissar M, Christensen B C, Kelsey K T, et al. MicroRNA expression ratio is predictive of head and neck squamous cell carcinoma[J]. Clin Cancer Res, 2009, 15(8): 2850-2855.
[10] 张春妮, 张辰宇. 体液microRNA作为新的无创伤性生物标志物的意义[J]. 分子诊断与治疗杂志, 2011, 3(3): 145-151. ZHANG Chunni, ZHANG Chenyu. The significance of humoral microRNA as a new biomarker for noninvasive biological[J]. J Mole Diagn Ther, 2011, 3(3): 145-151.
[11] 孙伟, 史冬泉, 蒋青. 血清microRNA的检测及临床应用进展[J]. 医学综述, 2011, 17(23): 3616-3618. SUN Wei, SHI Dongquan, JIANG Qing. Progress of detection and clinical application of serum microRNA[J]. Med Survey, 2011, 17(23): 3616-3618.
[12] Liu C J, Kao S Y, Tu H F, et al. Increase of microRNA miR-31 level in plasma could be a potential marker of oral cancer[J]. Oral Dis, 2010, 16(4): 360-364.
[13] Park N J, Zhou H D, Elashoff D, et al. Salivary microRNA: discovery, characterization, and clinical utility for oral cancer detection[J]. Clin Cancer Res, 2009, 15(17): 5473-5477.
[14] Siow M Y, Karen Ng L P, Vincent Chong V K, et al. Dysregulation of miR-31 and miR-375 expression is associated with clinical outcomes in oral carcinoma[J]. Oral Dis, 2014, 20(4): 345-351.
[15] Rather M I, Nagashri M N, Swamy S S, et al. Oncogenic microRNA-155 down-regulates tumor suppressor CDC73 and promotes oral squamous cell carcinoma cell proliferation: implications for cancer therapeutics[J]. J Biol Chem, 2013, 288(1): 608-618.
[16] Su J, Baigude H, McCarroll J, et al. Silencing microRNA by interfering nanoparticles in mice[J]. Nucleic Acids Res, 2011, 39(6): 38.
[17] 陈建, 王朝霞. 微小RNA: 肿瘤耐药治疗新靶点[J]. 现代肿瘤医学, 2012, 20(01): 191-196. CHEN Jian, WANG Zhaoxia. miRNA: Tumor drug resistance therapy target[J]. Mod Tumor Med, 2012, 20(1): 191-196.
[1] ZHAO Dongdong, WANG Yi, GAO Jianlu.. Common susceptibility genes of primary open-angle glaucoma. [J]. J Otolaryngol Ophthalmol Shandong Univ, 2017, 31(6): 92-96.
[2] SUN Feifei, HU Songqun, TANG Yan, ZHANG Jie, WU Di, QIU Jinhong, WANG Zhixia, ZHANG Luping. A next-generation sequencing gene panel for molecular diagnosis in twelve Chinese families with non-syndromic sensorineural hearing loss. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(5): 45-49.
[3] GENG Cong, ZHANG Liwei, DING Ming. The effect of general anesthesia on postoperative cognitive function in patients with simple snoring. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(5): 85-88.
[4] JI Shuaifei, ZHANG Jie, YAN Hong. Selection of intraocular lens for patients with age-related macular degeneration. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(4): 36-39.
[5] WANG Cui, YAN Xin, ZHAO Bojun. Combination of intravitreal ranibizumab with photodynamic therapy in the treatment of wet age-related macular degeneration. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(4): 94-97.
[6] CHENG Lei, QIAN Junjun, TIAN Huiqin. Research progresses on allergic rhinitis. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(3): 1-3.
[7] XU Yuanteng, CHEN Ruiqing, LIN Gongbiao, FANG Xiuling, YU Shujuan, LIANG Xiaohua, ZHANG Rong. Effect of silencing PDCD4 gene on proliferation of Hep-2 cells and the expression of β-catenin by RNA interference technique. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(5): 110-114.
[8] SONG Qi, TANG Juan, CAI Kejie, PANG Kunpeng, WEI Yan, XU Tonghui, ZHAI Yonghua. Comparison of allogeneic broad fascia preserved with different methods for ocular transplantation. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(5): 120-124.
[9] ZHANG Ruxin. Prospect and progress of allergic rhinitis. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(4): 3-6.
[10] TENG Weiqiang, CHEN Xiaoping, ZHANG Yan, ZHOU Enhui, YAO Wenhao, LI Li. Study on single nucleotide polymorphisms of partial allergic rhinitis-associated haplotype module genes. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(4): 26-29.
[11] ZHAO Lu, XIE Guoli, WANG Yanling. Changes of ocular hemodynamics after intravitreal ranibizumab injection in patients with wet age-related macular degeneration. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(4): 101-104.
[12] CHANG Jiangyi, MA Lingguo, LI Jianyu, ZHOU Jingchun, ZHOU Zhou, ZENG Fanqian, XU Yang. Experimental study on the construction of heterogeneous decellularized dermal matrix-free jejunal complex. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(3): 52-55.
[13] WANG Fengjuan, LI Chuangang, FAN Xianliang. General anesthesia without muscle relaxant for microsurgery of radical mastoidectomy (30 cases report). [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(4): 25-27.
[14] DU Xiangge, ZHANG Yingchun, YAN Xin, WANG Cui, ZHAO Bojun. In vitro study of the effect of Casein Kinase2 siRNA on anginogesis [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(3): 76-80.
[15] CHEN Chunli, SONG Zongming, JIA Xinguo, ZHOU Zhonglou, WANG Zhaoyang. Erythropoietin inhibits Müller cell apoptosis induced by oxidative damage [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(3): 65-71.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd