术前超声评估分化型甲状腺癌颈部淋巴结转移

doi:10.6040/j.issn.1673-3770.0.2018.443

Abstract

Abstract: Objective To investigate the clinical value of preoperative ultrasonography in detecting central compartment and lateral neck lymph node metastasis. Methods In total, 186 consecutive patients with pathologically proven differentiated thyroid cancer were involved in this retrospective study. All patients underwent operative US examination in the Department of Ultrasound and central-compartmental lymph node dissection in the Department of Otorhinolaryngology Head and Neck Surgery in Qilu Hospital of Shandong University(Qingdao), while 71 of them underwent lateral neck compartmental lymph node dissection between April 2017 and August 2018. According to the gold standard of biopsy, the sensitivity, specificity, positive predictive value(PPV), and negative predictive value(NPV)were calculated using SPSS 20.0 statistical software. All the patients were divided into two groups; groups A and B included patients with or without chronic lymphocytic thyroiditis(CLT). The sensitivity, specificity, PPV, and NPV of central neck compartmental lymph node metastasis detected using US were calculated. Results The sensitivity, specificity, PPV, and NPV of central compartmental lymph node metastasis detected using US were 68.9%, 56.3%, 75.0%, and 48.6%, respectively; those of lateral neck compartmental lymph node metastasis detected using US were 95.3%, 57.1%, 95.3%, and 57.1%, respectively. The sensitivity, specificity, PPV, and NPV in group A were 85.0%, 35.0%, 72.3%, and 53.8%, respectively; those in group B were 62.5%, 67.4%, 76.9%, and 50.8%, respectively. Conclusion Preoperative US for central and lateral neck lymph node metastasis is valuable for the management of cervical lymph node dissection. The diagnosis of lateral neck lymph node metastasis is much more accurate than that of central neck lymph node metastasis, while the diagnosis of central neck lymph node metastasis in patients with CLT is more accurate than that in patients without CLT.

Key words: Differentiated thyroid cancer, Ultrasound, Lymphatic metastasis, Chronic lymphocyte thyroiditis

CLC Number:

R445.1

GAO Xiaoqian, JIANG Zhen, GENG Chenchen, LIU Dayu, LI Li. Preoperative ultrasonography in detecting cervical lymph node metastasis in differentiated thyroid cancer[J].Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 135-139.

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Preoperative ultrasonography in detecting cervical lymph node metastasis in differentiated thyroid cancer

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