磁共振动脉自旋标记技术在缺血性疾病中的应用研究

doi:10.6040/j.issn.1673-3770.1.2020.053

Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2020, Vol. 34 ›› Issue (4): 16-22.doi: 10.6040/j.issn.1673-3770.1.2020.053

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The application of arterial spin labeling in ischemic diseasesZHOU Zhuohua Overview LI Hongyang, HUANG Yingxiang, WANG Yanling Guidance Department of Ophthalmology, Beijing Friendship Hospital affiliated to Capital Medical University, Beijing 100050, ChinaAbstract:

Arterial spin labeling(ASL)is a non-invasive imaging technique that permits the quantitative analysis of tissue perfusion without contrast agents, and it has been widely used in ischemic disease research. This paper introduces the application of ASL in the assessment of ischemic ophthalmopathy and encephalopathy and compares it with other common examination techniques of the eye and brain. ASL can be used to monitor changes in cerebral blood flow and predict ischemic events, and it has been widely used in the study of ischemic encephalopathy. It can directly reflect the dynamics of blood flow through the chorioretinal vasculature, and it can be used as a reliable method for quantifying ocular blood perfusion. ASL is also relevant for the pathophysiological studies of chorioretinal diseases, which may contribute to the early diagnosis of ischemic ophthalmopathies. Currently, the application of ASL in ophthalmology is still limited, and further studies are needed to establish the utility of ASL in assessing ischemic ophthalmopathy.

Key words: Ischemic ophthalmopathy;
Arterial spin labeling;
Ischemic encephalopathy;
Diagnosis;
Magnetic resonance imaging缺血性疾病(如缺血性眼病、缺血性脑病)具有高发病率的特点, 且部分早期症状不典型, 早期发现、早期诊断可使患者得到及时治疗, 对于降低致残率和死亡率具有重要意义。随着影像学技术的发展, 该类疾病的检查手段多种多样, 磁共振动脉自旋标记(arterial spin labeling, ASL)技术作为一项新的成像技术应用于缺血性疾病的早期诊断, 在有些方面已经取得了可见的成效。现就ASL在缺血性疾病中的临床应用进行综述。

Received:2020-05-29 Online:2020-07-20 Published:2020-08-28

Abstract

Abstract: Arterial spin labeling(ASL)is a non-invasive imaging technique that permits the quantitative analysis of tissue perfusion without contrast agents, and it has been widely used in ischemic disease research. This paper introduces the application of ASL in the assessment of ischemic ophthalmopathy and encephalopathy and compares it with other common examination techniques of the eye and brain. ASL can be used to monitor changes in cerebral blood flow and predict ischemic events, and it has been widely used in the study of ischemic encephalopathy. It can directly reflect the dynamics of blood flow through the chorioretinal vasculature, and it can be used as a reliable method for quantifying ocular blood perfusion. ASL is also relevant for the pathophysiological studies of chorioretinal diseases, which may contribute to the early diagnosis of ischemic ophthalmopathies. Currently, the application of ASL in ophthalmology is still limited, and further studies are needed to establish the utility of ASL in assessing ischemic ophthalmopathy.

Key words: Ischemic ophthalmopathy, Arterial spin labeling, Ischemic encephalopathy, Diagnosis, Magnetic resonance imaging

CLC Number:

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